GPU (Graphics Processing Unit)-based rapid optimization operation gene co-expression network method

A co-expression and gene technology, which is applied in the field of gene co-expression network based on GPU-based rapid optimization calculation, can solve the problems of low efficiency and difficulty of dimension reduction, reduce the analysis cycle, simplify the hardware and software environment, and shorten the analysis wait the effect of time
CN113920003APending Publication Date: 2022-01-11NANJING UNIV OF POSTS & TELECOMM
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANJING UNIV OF POSTS & TELECOMM
Publication Date
2022-01-11

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Abstract

The invention discloses a GPU (Graphics Processing Unit)-based rapid optimization operation gene co-expression network method, which belongs to the field of internet and comprises the following steps: 1, establishing a data reading module, a correlation matrix coefficient iteration module and a grade numerical value iteration module, providing computing power by using a GPU, and constructing the gene co-expression network; and 2, reading related data of the input file by using a data reading module. An iteration idea is introduced, and a new value is recursively calculated by using an old value, so that the new value can adapt to gene co-expression data under different conditions, and then a weighted association network is constructed and a result with more biological significance is obtained; and the GPU has multiple cores and is applied to gene co-expression network analysis to process a gene co-expression matrix, so that the analysis period can be greatly shortened, and the analysis waiting time can be shortened. In this way, needed hardware and software environments are simple, and installation is convenient.
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Description

technical field

[0001] The invention relates to the technical field of the Internet, in particular to a method for quickly optimizing and computing a gene co-expression network based on GPU. Background technique

[0002] Since gene co-expression data usually measure the expression values ​​of tens of thousands of genes in dozens of samples, for such a huge matrix, the calculation of gene data processing is extremely large and the efficiency is not high, so many bioinformatics tools have been developed Using network biology methods to analyze and mine high-throughput gene expression data has become an important research direction of bioinformatics. The gene co-expression matrix is ​​a multidimensional matrix, and the computational optimization of multidimensional matrices and complex networks has always been a hot topic for researchers at home and abroad.

[0003] Rudolph et al. conducted research on the directed WS small-world network model, and proposed a new analytical fr...

Claims

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