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Preparation method of cobra traditional Chinese medicine raw powder

A technology of cobra and traditional Chinese medicine, which is applied in the direction of medical formula, medical preparations containing active ingredients, powder delivery, etc. It can solve the problems of snake powder drug active ingredient damage, etc., and achieve short sterilization time, high powder extraction rate and small impact Effect

Pending Publication Date: 2022-03-15
湖南永州异蛇生物制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The sterilization method adopted in this method is moist heat sterilization, but this method will damage the active ingredients of snake powder

Method used

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  • Preparation method of cobra traditional Chinese medicine raw powder
  • Preparation method of cobra traditional Chinese medicine raw powder
  • Preparation method of cobra traditional Chinese medicine raw powder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A preparation method of cobra Chinese medicine raw powder, comprising the following steps:

[0040] S1: Crushing: Weigh 300g of cobra decoction pieces produced in Guangxi, dry them until the water content is 6%, and the drying temperature is 65°C, then put them into the FL-150 dust collector for crushing, and then put them into the ultrafine crushing equipment to continue crushing , to obtain a fine powder, the particle size of the coarsely crushed powder is 50 mesh, and the particle size of the fine powder is 110 mesh;

[0041] S2: Sterilization: The fine powder obtained in the above S1 is sterilized by irradiation sterilization, using 60 Co-γ irradiation sterilization method, the irradiation dose is 6 kGy, and the sterilized fine powder is obtained;

[0042] S3: Packing: Pack the fine powder obtained in the above S2 treatment with a polyester / aluminum foil / polyethylene medicinal composite film to obtain a finished cobra medicinal powder.

Embodiment 2

[0044] A preparation method of cobra Chinese medicine raw powder, comprising the following steps:

[0045]S1: Grinding: Weigh 300g of cobra decoction slices produced in Yongzhou, dry to 7% water content, and the drying temperature is 60°C, then put it into the FL-150 dust collector for grinding, and then put it into the ultrafine grinding equipment to continue grinding , to obtain a fine powder, the particle size of the coarsely crushed powder is 40 mesh, and the particle size of the fine powder is 120 mesh;

[0046] S2: Sterilization: The fine powder obtained in the above S1 is sterilized by irradiation sterilization, using 60 Co-γ irradiation sterilization method, the irradiation dose is 6 kGy, and the sterilized fine powder is obtained;

[0047] S3: Packing: Pack the fine powder obtained in the above S2 treatment with a polyester / aluminum foil / polyethylene medicinal composite film to obtain a finished cobra medicinal powder.

Embodiment 3

[0049] A preparation method of cobra Chinese medicine raw powder, comprising the following steps:

[0050] S1: Crushing: Weigh 300g of cobra decoction pieces produced in western Hunan, dry them until the water content is 7%, and the drying temperature is 70°C, then put them into the FL-150 dedusting pulverizer for pulverization, and then put them into the superfine pulverization equipment to continue pulverization , to obtain a fine powder, the particle size of the coarsely pulverized powder is 48 mesh, and the particle size of the fine powder is 100 mesh;

[0051] S2: Sterilization: The fine powder obtained in the above S1 is sterilized by irradiation sterilization, using 60 Co-γ irradiation sterilization method, the irradiation dose is 6 kGy, and the sterilized fine powder is obtained;

[0052] S3: Packing: Pack the fine powder obtained in the above S2 treatment with a polyester / aluminum foil / polyethylene medicinal composite film to obtain a finished cobra medicinal powder....

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Abstract

The invention discloses a preparation method of cobra traditional Chinese medicine raw powder, and belongs to the technical field of medicine powder processing, and the preparation method comprises the following steps: crushing: taking cobra decoction pieces, drying until the handfeel is dry, then putting into crushing equipment for crushing, and then putting into superfine crushing equipment for continuously crushing to obtain fine powder; s2, sterilization: sterilizing the fine powder obtained in the step S1 by adopting an irradiation sterilization method to obtain sterilized fine powder; and packaging: packaging the fine powder treated in the step S2 with a medicinal composite film to obtain a finished cobra powder product. The cobra traditional Chinese medicine raw powder fine powder prepared by the method is high in powder yield and complete in effective components, and the microbial limit of the cobra traditional Chinese medicine raw powder fine powder meets the microbial limit standard of traditional Chinese medicine decoction pieces in non-sterile product microbial limit inspection in the general rule of Chinese pharmacopoeia in 2020 edition 4; the water content and the total ash content conform to the second method 0832 of the four-part general rule of the Chinese pharmacopoeia 2020 edition and the provision 2302 of the four-part general rule of the Chinese pharmacopoeia 2020 edition.

Description

technical field [0001] The invention belongs to the technical field of medicinal powder processing, and in particular relates to a preparation method of raw cobra traditional Chinese medicine powder. Background technique [0002] Cobra is also called swollen-necked snake, bat snake, five poisonous snake, and lute snake. It is a cobra of the Cobra family. Body length 1-2m, stout; head oval, head and body back dark brown, neck with speckled markings, body back yellowish white to taupe. No buccal scales, 1 preorbital scale, 2 or 3 retroorbital scales; 2+3 temporal scales, 2-2-3 upper lip scales; smooth dorsal scales, 23-21 (19)-15 lines; ventral scales 160-196 ; 2 points for anal scales, 38 to 54 pairs of subcaudal scales. The processing of cobras is mostly to remove the internal organs, dry the blood, and use them fresh or dry. The standards of Chinese medicinal materials in one province, municipality and autonomous region of the country include cobra, and its processing me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/583A61K9/14A61L2/08
CPCA61K35/583A61K9/14A61L2/0035
Inventor 丁野谭群英方磊李跃辉郭德志郭德刚潘希
Owner 湖南永州异蛇生物制药有限公司
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