53results about How to "Good cough suppressant" patented technology

The invention discloses dextromethorphan orally disintegrating tablets and a preparation method thereof. The dextromethorphan orally disintegrating tablets are prepared from the following main raw materials in part by weight: 2 to 8 parts of dextromethorphan, 8 to 12 parts of lactose, 50 to 70 parts of mannitol, 60 to 70 parts of microcrystalline cellulose, 10 to 20 parts of crosslinked PVP, 10 to 20 parts of crosslinked CMC-Na, 2 to 8 parts of Aspartame, 1 to 5 parts of Eudragit E100 and 1 to 5 parts of talcpowder. The method of the invention comprises the following steps: firstly, preparing film-coated granules; secondly, preparing blank granules; finally, uniformly mixing the prepared film-coated granules, the prepared blank granules and additional auxiliary materials in part by weight including 0.1 to 0.3 part of menthol, 1 to 4 parts of magnesium stearate, 10 to 20 parts of 10 to 20 parts of and 2 to 10 parts of essence; and tabletting the mixture and obtaining the dextromethorphan orally disintegrating tablets. The dextromethorphan orally disintegrating tablets of the invention are simple in technical control, fast in absorption, high in bioavailability and convenient in administration.

The invention provides a traditional Chinese rice-pudding with oak leaves as an outer wrappage and a preparation method thereof. The oak leaf is used as the outer wrappage of the traditional Chinese rice-pudding, so that the manufactured traditional Chinese rice-pudding has good flavor and can be preserved for a long time without deteriorating; and meanwhile, a plurality of physiological activators contained in the oak leaf can be used for realizing the healthcare function. The millet with rich nutrition and health-preserving function is used as the main raw materials of the traditional Chinese rice-pudding to combine with the oak leaf to prepare the traditional Chinese rice-pudding, thereby enabling the traditional Chinese rice-pudding to possess good health-care effect while possessing good flavor. Furthermore, the traditional Chinese rice-pudding manufactured by the method is novel in shape, and capable of providing comprehensive enjoyment from vision to taste for a consumer.

The invention relates to a bechic medicine, especially to an intensified loquet distillate and its preparation method. The intensified loquet distillate provided by the invention comprises the following components of: by weight, 50 g of loquat leaf, 45 g of opium poppy shell, 10 g of radix stemonae, 6 g of cynanchum root and rhizome, 4 g of mulberry bark, 4 g of balloonflower root and 0.09 g of menthol. The preparation method comprises the following steps of: adding water into six components of loquat leaf and the like except menthol, decocting for two times with 2.5 hours for each time, merging the decoctions, filtering, condensing to 700 ml, adding 2.6 g of sodium benzoate, stirring until it is dissolved, adding 700 g of cane sugar, keeping heating to boiling, insulating for 30 min, standing, filtering, adding water to 1200 ml, and uniformly mixing to obtain the intensified loquet distillate. The intensified loquet distillate provided by the invention has effects of nourishing yin, astringing lung, relieving cough and eliminating sputum, and has a good cough-relieving function.

A dahurian rhododendron softgel for treating cough and asthma and dispelling phlegm is prepared from dahurian rhododendron through distilling to extract volatile oil, extracting from dregs in alcohol, recovering alcohol, mixing, concentrating, adding auxiliaries, superfine pulverizing and die pressing.

The invention relates to a hydantoin ibuprofen derivative and a synthetic method and application thereof, belonging to the field of medicaments. The synthetic method comprises the following steps of: heating and refluxing twice dose of ibuprofen and quintuple dose of thionyl chloride for 3 hours and evaporating to dryness; and adding an appropriate amount of pyridine and 1.2 times dose of hydantoin derivative, reacting at room temperature for 12 hours, evaporating to dryness, and performing chromatography to obtain a 3-(2-(4-isobutyl phenyl) propiono) imidazolidinyl-2,4-diketone derivative. As proved by a pharmacological test, the compound has higher anti-inflammatory activity than ibuprofen serving as a control medicament, and has high cough relieving activity simultaneously.

The invention discloses a preparation method of a Huang Long cough and asthma capsule. The preparation method includes the steps of: 1) preparing fine powder A by mixing six medicines including astragalus membranaceus, earthworms, herba epimedii, herba ephedra, belamcanda sinensis and semen lepidii; 2) preparing fine powder B by mixing three medicines including houttuynia cordata, platycodon grandiflorum and hawthorns; 3) uniformly mixing the fine powder A and the fine powder B, adding proper amounts of silica gel micropowder and starch, granulating the mixture and sieving the mixture, and filling capsules with the mixture to obtain the Huang Long cough and asthma capsule. In the preparation method, due to the grouped extraction process, active components are enriched while some useless components are rejected, so that curative effect of the capsule is improved and dose of the capsule is reduced. Compared with a reference group produced through conventional processes, the Huang Long cough and asthma capsule has strong effects even the dose is reduced by 50%.

The invention provides a lung-moistening and cough-relieving tea drink. The tea drink is characterized by comprising the following raw materials by weight: 8 to 12 parts of perilla leaf, 20 to 40 parts of ginseng, 2 to 8 parts of dwarf lilyturf tuber, 20 to 40 parts of Poria cocos, 2 to 5 parts of Chinese thorowax root, 10 to 15 parts of mint, 10 to 30 parts of Plantain seed, 3 to 10 parts of licorice and 1 to 3 parts of coix seed. The above-mentioned nine traditional Chinese medicines are easily available and need low cost; the lung-moistening and cough-relieving tea drink exerts the effects of clearing lung-heat, moisturizing dryness, benefiting lung-qi, reducing phlegm and relieving cough when people drinking the tea drink; and the tea drink has good taste and is convenient to drink.

The invention discloses a Chinese medical composition capable of resolving phlegm and relieving asthma and a preparation method thereof, belonging to the field of modernization of traditional Chinese medicines. The active ingredients of the Chinese medical composition capable of resolving phlegm and relieving asthma is prepared from the following raw materials in parts by weight: 75 parts of chrysoidine, 100 parts of calyx seu fructus physalis, 75 parts of bulbus fritillariae cirrhosae, 100 parts of fried bitter almond, 75 parts of fruit of poppy capsules, 75 parts of shizandra berries, 75 parts of white vitriol and 75 parts of liquorice. The invention has the advantages of stable and controllable quality, remarkably improved curative effect as compared with a currently marketed preparation, reduced patient administration dosage and improved bioavailability and has remarkable economic and social benefits.

The invention discloses a composition with a cough-relieving effect, which is prepared from the raw medicinal materials including 10-15 parts of loguat leaf, 10-15 parts of unibract fritillary bulb, 5-10 parts of dried tangerine or orange peel, 5-10 parts of platycodon root, 5-10 parts of bamboo shavings, 2-5 parts of glehnia root, 2-5 parts of snakegourd seed, 2-5 parts of polygala root and 2-5 parts of liquorice. The composition is prepared by reasonably matching and combining different herbal medicines and has an obvious cough-relieving effect and good safety.

The invention provides an apios americana tuber compound beverage and a preparation method thereof. The apios americana tuber compound beverage provided by the invention is prepared from apios americana tuber or apios americana tuber together with fructus momordicae, licorice roots and honey. The preparation method comprises the following steps: cutting the apios americana tuber into slices, and performing water-isolated heating or stewing on the apios americana tuber slices solely or performing water-isolated heating or stewing on the apios americana tuber slices together with the fructus momordicae, the licorice roots and the honey so as to obtain raw juice; adjusting the pH to be acidic, and then, performing flocculation; performing centrifugation after flocculation, and taking supernatant liquid; and adding a flavoring agent and a stabilizing agent, and performing high pressure homogenization, sterilization and filling to obtain the apios americana tuber compound beverage. The apios americana tuber compound beverage provided by the invention is rich in nutritional components, has the effects of clearing and moistening the throat, loosening the bowels to relieve constipation, reducing blood glucose and the like, has low calorie, is sugar-free and is suitable for diabetic patients to take.

The invention provides a traditional Chinese medicine composition for treating coughing and excessive phlegm. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine materials by weight percent: 3%-15% of rhizoma pinellinae praeparata, 3%-15% of flos farfarae (fried with honey), 3%-15% of ginkgo, 3%-15% of bulbus fritillariae cirrhosae, 3%-15% of pericarpium citri reticulatae, 1%-10% of fructus aurantii (fried), 1%-10% of liquorice, 1%-10% of the root bark of white mulberry (fried with honey), 1%-10% of snakegourd seed (fried), 1%-10% of fructus perillae (fried), 1%-10% of lily, and 10%-50% of ephedra. The coughing-relieving pharmacodynamic test of the traditional Chinese medicine composition is conducted, 90 cases of patients participate in the clinical test, and the result shows that the traditional Chinese medicine composition has a remarkable effect of treating the coughing and excessive phlegm, and can be used to prepare a medicine for preventing and treating the cough and excessive phlegm. The raw materials of the traditional Chinese medicine composition are easy to get, the traditional Chinese medicine composition is high in safety, has good effects, and has a better clinical application prospect. A preparation method is suitable for industrial production, and has a higher application value.

The invention relates to a sea buckthorn cough-relieving oral liquid and a preparation method thereof. In the method, the sea buckthorn cough-relieving oral liquid is prepared by taking sea buckthorn berry normal juice as the main raw material through the steps of: mixing the sea buckthorn berry normal juice with winter pear fruit juice, crystal sugar, semen coicis and unibract fritillary bulb extracting solution and honey in weight ratio, mixing uniformly and then loading into a cleaned and disinfected storage tank; adding purified water, and stirring uniformly; disinfecting at the high temperature of 110-130 DEG C for 10-20s and then quantitatively filling by using a filling machine. The invention has simple preparation method, used raw materials are uniformly and not polluted have wide source range, which is beneficial to industrialized production. Shown by tests on mice ammonia water tussigenic and human body antitussive effect, the oral liquid prepared by the method has obvious cough-relieving effect and no toxic or side effects, is portable and is convenient to take.

The invention discloses a total volatile oil extractive of asarum, an extraction method of the total volatile oil extractive and an application of the total volatile oil extractive in preparation of drugs for treating chronic coughs, belongs to the field of natural drugs and discloses a total volatile oil extractive of asarum as well as an extraction method and application of the total volatile oil extractive. The method comprises the steps of placing coarse asarum powder into an extraction kettle of a supercritical CO2 extraction device, and sealing; heating, opening a valve of the extraction kettle when the temperature of the extraction kettle is up to 45-70 DEG C, opening a vent valve to empty air and pressurizing a system when the pressure inside the extraction kettle is equal to that of a storage tank, and controlling the flow rate of CO2 at 35-60L / h and beginning to circularly extract when the pressure of the extraction kettle is up to 30-40Mpa, the pressures of a separation kettle I and a separation kettle II are up to 5-10Mpa and the separation temperature is up to 30-50 DEG C; and after extracting for 60-240 minutes, receiving the extracted total volatile oil extractive of asarum from discharging holes of the separation kettles. A great number of pharmacodynamic tests prove that the total volatile oil extractive of asarum has a remarkable effect on treatment of various chronic coughs and can be used for preparing drugs for treating corresponding diseases.

The invention discloses a compound combination medicine for treating a postinfectious cough and a preparation method of the compound combination medicine. The compound combination medicine is prepared from the following raw materials in parts by weight: 3-9 parts of herba periliae, 3-6 parts of periostracum cicada, 3-10 parts of honey-fried ephedra, 10-20 parts of denophora tetraphylla, 6-15 parts of pinellia ternate, 6-15 parts of cynanchum glaucescens, 5-12 parts of stemona, 6-15 parts of tatarian aster root, 10-30 parts of cudweed, 2-6 parts of scorpio and 3-6 parts of liquorice. According to the invention, based on the pathogenesis of cold and cough, treatment based on syndrome differentiation is carried out by screening a lot of experiment researches under the guidance of the theory of traditional Chinese medicines; the composition is combined by the traditional Chinese medicines which are mainly used for dispelling wind and ventilating the lung; a clinical experiment proves that the compound combination medicine has a good cough relieving effect; an animal experiment research also proves that the compound combination medicine disclosed by the invention has obvious effects of relieving the cough and removing the phlegm, and the effects of resisting inflammatory factors released by inflammation, and reducing bronchial hyperresponsiveness; and the compound combination medicine disclosed by the invention is safe, reliable, and low in adverse reaction.

The invention discloses a method for making dried persimmons with walnuts for health care and cough relief. The walnut fruit with plump kernels, after being dried in the sun, loses its astringency and stir-fries. First, stir-fry it with high heat. Spread the dried persimmon inside for 5 days in a cool place to soften the dried persimmon; after the soluble sugar in the dried persimmon forms persimmon frost on the surface of the dried persimmon and the walnut kernels fully absorb the sugar in the dried dried persimmon, seal the dried dried persimmon for preservation. This product absorbs calcium and other trace elements and active substances from various raw materials, so that it contains more calcium, trace elements beneficial to the human body and other active substances beneficial to the human body. Therefore, its nutrition is relatively comprehensive, It not only has the effect of supplementing calcium, but also has a good cough-relieving effect.

The invention relates to a plaster, in particular to a plaster for relieving a cough and a preparation method of the plaster. A specific formula of the plaster comprises 80 to 130 parts of hyssop, 80 to 130 parts of liquoric root, 15 to 50 parts of liquoric paste and 5 to 20 parts of borneol. A finished product is obtained through a soaking process, a heating process and other processes. The plaster has an obvious cough relieving function, and is short in treatment course, and quickly effective; the cough is not prone to relapse; raw materials are low in cost; the plaster is cheap; the preparation method is simple; toxic and side effects are eliminated; the burden and the disease of a patient can be effectively alleviated; the cure rate reaches 96.6 percent, and the symptomatic unsuitable rate is smaller than 5 percent, which is lower than that of other medicines.

The invention discloses a preparation method of fructus momordicae health wine. The preparation method comprises the following steps: preparing fructus momordicae raw liquid; mixing the raw liquid andleaching liquid of maca, ginseng, burdock, medlar, jujubes, gecko tails, male silkworm moths and yam; mixing the mixed raw liquid, honey and crystal sugar, filtering, clarifying and aging to obtain the health wine. The health wine prepared by the preparation method disclosed by the invention has good liver-protecting and kidney-tonifying effects.

The invention discloses a compound as shown in a formula (I), or a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvent compound, a metabolite and a pharmaceutically acceptable salt of the compound as shown in the formula (I). The invention also provides application of the compound, the stereoisomer or the pharmaceutically acceptable salt thereof in preparation of drugs for treating and / or preventing diseases related to TRPA1 receptors, especially application in preparation of drugs for treating and / or preventing cough, asthma, pain and sleep apnea.

The invention discloses meal replacement powder for improving phlegm-dampness constitution, which is prepared from, by weight, 2-4 parts of lotus leaves, 5-8 parts of red beans, 1-3 parts of poria cocos, 1-3 parts of mint, 4-6 parts of black soybeans, 1-3 part of raw hawthorns, 8-12 parts of husked sorghum, 1 part of platycodon grandiflorum, 1 part of kudzu vine roots and 1 part of cinnamon. A preparation method comprises the steps: S1, washing the raw materials, and then executing the step S2; S2, weighing 1 part of platycodon grandiflorum, adding 9 parts of water, executing soaking for 30 minutes, executing decoction with medium fire for 30 minutes, and taking and stir-frying 5 parts of medicinal juice obtained after decoction and 1-3 parts of mint with small fire for 5-10 minutes; weighing 1 part of kudzu vine roots, adding 9 parts of water, executing soaking for 30 minutes, executing decoction with medium fire for 30 minutes, and taking 5 parts of medicinal juice obtained after decoction and 24 parts of lotus leaves, 5 parts of red beans and executing stir-frying with small fire for 5-10 minutes. The powder integrates medicines and foods, can be taken for a long time, does nothave toxic or side effects, not only can promote hydration and dampness, but also can invigorate the spleen, has the effect of eliminating phlegm, has the very good effect on dredging a waterway, gives consideration to upper, middle and lower jiao, and is beneficial to the lung, spleen and kidney.

The invention relates to a traditional Chinese medicine composition for treating cough, made from 3-15 parts of mulberry silkworm, 3-15 parts of cicada slough, 5-15 parts of roasted herb of Chinese ephedra, 5-15 parts of apricot seed, 5-15 parts of roasted loquat leaf, 5-15 parts of roasted root of sessile stemona, and the like. The traditional Chinese medicine composition can effectively treat cough due to various causes, has light side effects, and can effectively treat, particularly, cough variant asthma, acute bronchitis, and gastro-esophageal reflux induced cough.

The invention provides compound ardisia japonica syrup for treating lung heat yin deficiency cough and a preparation method of the syrup, and belongs to the technical field of traditional Chinese medicines. Every 1000ml of syrup is prepared from the following main raw materials by weight, 65-90g of ardisia japonica, 30-50g of lily, 65-90g of selfheal spike, 20-40g of codonopsis pilosula and an appropriate quantity of flavoring agents. The syrup has the functions of clearing heat, resisting tuberculosis, moistening lung, relieving cough, invigorating spleen and dispersing accumulations and is applicable to patients suffering from cough, expectoration, hemoptysis, night sweat and emaciation of traditional Chinese medicine syndrome differentiation lung heat yin deficiency such as tuberculosis, tuberculous lymphadenitis, bronchiectasis, bronchitis, chronic obstructive pulmonary disease, pneumonia and infantile malnutrition. The syrup is simple in formula, definite in therapeutic effect and low in medicine cost and can widely obtain market recognition, and raw materials are easily obtained.

The invention relates to an application method of a soft capsule containing sheep placenta, radix salviae miltiorrhizae and grape seeds, namely, an application of the soft capsule containing sheep placenta, radix salviae miltiorrhizae and grape seeds in preparing a cough medicine, and specifically, sheep placenta freeze-dried powder, grape seed extract, radix salviae miltiorrhizae extract, soybean oil, beewax, gelatin and glycerinum are adopted as raw materials, and subjected to the main procedures including smashing, mixing, homogenizing, pelleting, drying and the like to prepare the cough medicine. The cough medicine prepared by the soft capsule containing sheep placenta, radix salviae miltiorrhizae and grape seeds is significant in cough relieving effect, and has an obvious effect in alleviating the cough symptom of the cough variant asthma.

The invention discloses a Chinese medical composition capable of resolving phlegm and relieving asthma and a preparation method, belonging to the field of modernization of traditional Chinese medicines. The Chinese medical composition capable of resolving phlegm and relieving asthma is prepared from the following raw materials in parts by weight: 75 parts of chrysoidine, 100 parts of wintercherry fruit or calyx, 75 parts of bulbus fritillariae cirrhosae, 100 parts of fried bitter almond, 75 parts of fruit of poppy capsules, 75 parts of shizandra berries, 75 parts of white vitriol and 75 parts of liquorice. The invention has the advantages of stable and controllable quality, remarkably improved curative effect as compared with a currently marketed preparation, reduced patient administration dosage and improved bioavailability and has remarkable economic and social benefits.

The invention provides a preparation method of corn stigma drinks. Corn stigma water has a good health care function, but such kind of product is lacked on the market at present, which seriously affects the use of people needing the product. The preparation method of corn stigma drinks comprises the following steps: 1. selecting and washing corn stigmas; 2. adding water to cook the corn stigmas; 3. adding ingredients; 4. carrying out distillation; 5. carrying out filling; 6. carrying out high temperature sterilization; 7. carrying out inspection and warehousing. The preparation method is used for preparing corn stigma drinks.

The invention discloses a compound as shown in a formula (I), or a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvent compound, a metabolite and a pharmaceutically acceptable salt of the compound as shown in the formula (I). The invention also provides application of the compound, the stereoisomer or the pharmaceutically acceptable salt thereof in preparation of drugs for treating and / or preventing diseases related to TRPA1 receptors, especially application in preparation of drugs for treating and / or preventing cough, asthma, pain and sleep apnea.

The invention provides a folium sauropi extract with anti-inflammatory and antitussive effects. The provided folium sauropi extract is extracted from the leaf portion of the folium sauropi from the euphorbiaceae and can be used for preparing medicines for inflammation resistance, lung-heat cough and panting and excessive phlegm, asthma, internal injury, tuberculosis and aphonia, laryngalgia and the like; in addition, the folium sauropi extract has the advantages of low toxicity, small side effects and simplicity and convenience in operation of preparation process, low production cost and suitability for large-scale industrial production. The invention also relates to a folium sauropi extract preparation. The folium sauropi extract preparation has the advantages of being obvious in anti-inflammatory and antitussive effects, convenient to take and the like.

The invention belongs to the technical field of leisure foods and particularly relates to a pearl plum fruit cake and a preparation method thereof. The pearl plum fruit cake is prepared from the following raw materials in parts by weight: 3-8 parts of pearl plums, 2-5 parts of starch, 35-40 parts of white sugar, 35-40 parts of maltose syrup, 2-3 parts of citric acid, 1-2 parts of malic acid, 2-5 parts of citron leaves and 100-120 parts of water. The pearl plum fruit cake is refined by taking the pearl plums, the citron leaves, the white sugar, the maltose syrup and the starch as the raw materials, is convenient to eat and high in content of the pearl plum component, is sweet and delicious and has the action of moistening lung to arrest cough, thus being a fruit preserve with better health function.

The invention relates to a traditional Chinese medicine composition for treating cough. The raw materials include 3-15 parts of silkworms, 3-15 parts of cicada sloughs, 5-15 parts of roasted ephedra, 5-15 parts of almonds, 5-15 parts of sun-baked papaya leaves and sun-baked 5‑15 copies of 100 parts, etc. The traditional Chinese medicine composition has good therapeutic effect on coughs caused by various reasons and has mild side effects. Especially for the treatment of cough variant asthma, acute bronchitis and gastroesophageal reflux cough have a better effect.