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Preparation method of Huang Long cough and asthma capsule

A cough and asthma and capsule technology, which is applied in the field of preparation of Chinese patent medicines, can solve the problems of not being able to give full play to the efficacy of the medicine and the low efficiency of the extraction method, and achieve the effects of improving the efficacy of the product, reducing the frequency of coughing, and having a good antitussive effect

Active Publication Date: 2017-12-01
SHAANXI DONGKE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the problems existing in the prior art, the purpose of the present invention is to provide a new preparation method of Huanglong Kechuan Capsules, which solves the problem that the existing extraction method is inefficient and cannot fully exert the drug effect

Method used

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  • Preparation method of Huang Long cough and asthma capsule
  • Preparation method of Huang Long cough and asthma capsule
  • Preparation method of Huang Long cough and asthma capsule

Examples

Experimental program
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Effect test

Embodiment 1

[0101] The present embodiment provides a kind of preparation method of Huanglong Kechuan Capsules:

[0102] 1) Prescription: Astragalus 225g, Earthworm 75g, Epimedium 250g, Jinghawthorn 375g, Campanulaceae 75g, Houttuynia cordata 500g, Shegan 150g, Honey Ephedra 75g, Tinglizi 150g;

[0103] 2) Nine medicinal materials such as Astragalus membranaceus and Earthworm in the prescription are cleaned and processed, and then divided into two groups.

[0104] ① Astragalus, Earthworm, Epimedium, Ephedra, Shegan, and Tinglizi are extracted three times under reflux with water; the extracts are combined, filtered, and the filtrate is concentrated under reduced pressure (-0.04Mpa, 70°C) to a relative density of 1.08~ 1.12 (60°C) thick paste, add a certain amount of ethanol, let it stand, filter, the filtrate is decompressed (-0.04Mpa, 70°C) to recover ethanol and concentrate until it has no alcohol smell, dry, and pulverize into fine powder A;

[0105] ② Houttuynia cordata, Platycodon gra...

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Abstract

The invention discloses a preparation method of a Huang Long cough and asthma capsule. The preparation method includes the steps of: 1) preparing fine powder A by mixing six medicines including astragalus membranaceus, earthworms, herba epimedii, herba ephedra, belamcanda sinensis and semen lepidii; 2) preparing fine powder B by mixing three medicines including houttuynia cordata, platycodon grandiflorum and hawthorns; 3) uniformly mixing the fine powder A and the fine powder B, adding proper amounts of silica gel micropowder and starch, granulating the mixture and sieving the mixture, and filling capsules with the mixture to obtain the Huang Long cough and asthma capsule. In the preparation method, due to the grouped extraction process, active components are enriched while some useless components are rejected, so that curative effect of the capsule is improved and dose of the capsule is reduced. Compared with a reference group produced through conventional processes, the Huang Long cough and asthma capsule has strong effects even the dose is reduced by 50%.

Description

technical field [0001] The invention belongs to the technical field of preparation of Chinese patent medicines, relates to a preparation process of Chinese patent medicines, in particular to a method for extracting and preparing Huanglong Kechuan Capsules (WS-10055(ZD-0055)-2002-2015). Background technique [0002] Asthma is a common chronic respiratory disease, and its prevalence is increasing year by year worldwide. It is an immune abnormality characterized by reversible airway obstruction, airway hyperresponsiveness and airway inflammation caused by multiple factors. Reactive disease, an inflammatory response involving a variety of inflammatory cells and structural cells (such as eosinophils, mast cells, T lymphocytes, neutrophils, smooth muscle cells, airway epithelial cells, etc.), cough, cough Symptoms such as phlegm, wheezing, shortness of breath, and wheezing in the throat belong to the category of "asthma" in traditional Chinese medicine. [0003] Huanglong Kechuan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/48A61P11/00A61P11/06A61P11/14A61P11/10A61K35/62
CPCA61K9/1652A61K35/62A61K36/17A61K36/296A61K36/31A61K36/346A61K36/481A61K36/734A61K36/78A61K36/88A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 杜杉夏传涛
Owner SHAANXI DONGKE PHARMA
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