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Technology for producing Dekuiluan lozenge

A technology of dequinium chloride and production process, applied in the field of production technology of dequinium chloride buccal preparations, can solve the problems of uneven content of main drug, easily broken containing chemical, short containing time, etc., and achieves high uniformity , The effect of tablet hardness and long time of containing

Inactive Publication Date: 2005-07-20
TONGJI MINGZHI MEDICINE WUHAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So as to solve the preparation defects that cannot be solved by conventional technology
Insufficiencies such as short containing time, easy to break when containing, uneven content of main ingredients, etc.

Method used

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  • Technology for producing Dekuiluan lozenge
  • Technology for producing Dekuiluan lozenge

Examples

Experimental program
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Effect test

Embodiment Construction

[0014] The implementation of the present invention is described in detail below in conjunction with accompanying drawing:

[0015] The present invention is implemented under normal pressure, and does not need a catalyst and has no special requirements on temperature.

[0016] The key steps of the production process of the dequalinium chloride buccal preparation of the present invention are: double dispersing, mixing and granulating.

[0017] Double dispersion: the main drug and auxiliary materials are diluted and mixed in an equal gradient, and after solid-solid mixing, solid-liquid mixing, liquid-liquid mixing, and liquid-solid mixing, the main drug of this product is evenly diluted to 1:240 (weight ratio ), to ensure that the uniformity of the main drug of this product meets the national statutory standard (Pharmacopoeia of the People's Republic of China 2000 edition).

[0018] Mixing: Add the double-dispersed material to the refined castor sugar in a ratio of 1:25 (weight ...

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PUM

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Abstract

The production process of dequalinium chloride lozenge successively includes: preparing material, mixing, granulating, drying, mixing, tabletting, metal inspection, foil wrapping and packaging. Said invented production process can be extensively used for producing various lozenge preparations using western medicine as main medicine for curing and preventing the disease of stomatitis, laryngopharyngitis and tonsillitis, etc.

Description

technical field [0001] The present invention relates to a kind of production technology of pharmaceutical preparation, more specifically it is a kind of production technology of dequalinium chloride buccal preparation. Background technique [0002] At present, most of the buccal tablets produced by domestic pharmaceutical factories are mainly Chinese patent medicines, which are made through conventional tabletting processes (weighing-mixing-granulation-granulation-compression-packaging), and this type of buccal tablets has curative effect Unclear, bitter taste, poor taste, dysphagia, patient’s teeth stained after medication, etc.; there are also a small number of buccal tablets with western medicine as the main drug, which are processed by conventional tableting process (weighing—mixing—granulation—whole grain— Although the curative effect of this type of lozenge is relatively clear, there are still shortcomings such as short time of containing, easy to...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K31/47A61K31/4706A61P1/02A61P11/04
Inventor 赵勇赵砥常学军
Owner TONGJI MINGZHI MEDICINE WUHAN