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Technique for preparing herbal medicine of seseli mairei Wolff

A preparation process and technology of bamboo leaves, applied in the field of medicine, can solve the problems of increased drowsiness and the like, and achieve the effects of no toxic and side effects and long-term use of toxic and side effects.

Inactive Publication Date: 2006-07-12
苏州玉森新药开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these antiallergic drugs have some adverse reactions, such as: the safety margin between the therapeutic dose and the poisoning dose of antihistamines is relatively large, the most common is the sedative effect of the drug, sleepiness during the day, most patients can Uncomfortable within a few days, while drinking alcohol or taking other central nervous system depressants (such as sedative hypnotics, antidepressants), can make drowsiness worse; the next common side effects are gastrointestinal symptoms, including loss of appetite, nausea and vomiting, abdominal discomfort , constipation, diarrhea and other adverse reactions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0012] Example 1: Extraction process of zephyr essential oil:

[0013] Take 10kg of bamboo leaf celery, put it in a volatile oil extractor, add 30kg of water, heat and reflux until no volatile oil flows out, encapsulate the extracted volatile oil with soft capsules, and make a preparation equivalent to 5 grams of raw materials per 1 soft capsule. .

example 2

[0014] Example 2: Preparation process of bamboo leaf zephyr granules:

[0015] Take 10 kg of celery celery, decoct twice with 5 times the amount of water, filter the water extract, precipitate with 80% alcohol, filter, and evaporate the solvent from the alcohol precipitation solution to obtain an extract, add 2 times the amount of auxiliary materials to obtain granules, Every 10 grams of granule is packed into a small bag, take three times a day, one small bag each time.

example 3

[0016] Example 3: Preparation process of capsules of active parts of celery lactones from bamboo leaf zephyr:

[0017] Take 10kg of celery celery, add 5 times the amount of water to decoct twice, filter the water extract, concentrate to obtain a paste, dissolve the paste with a small amount of water, extract twice with an equal volume of ethyl acetate, discard the ester layer, and remove the water layer Use hydrochloric acid to adjust the pH to 6, then extract twice with equal volume of ethyl acetate, collect the ester layer, wash with water until neutral, evaporate the solvent to obtain a solid extract, add appropriate amount of auxiliary, fill capsules, and make each capsule containing Capsules of about 0.2g of lactone.

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PUM

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Abstract

A Chinese medicine in the form of volatile oil, particle, or capsule for treating anaphylactia is prepared from a Chinese-medicinal materials: wingleaf Xifengqin through extracting in water, depositing in alcohol, concentrating and shaping. Its advantage is no toxic by-effect.

Description

[technical field] [0001] The invention relates to the technical field of medicine, in particular to a preparation process and application of the herbal medicine zephyr. [technical background] [0002] Anaphylaxis is an allergic disease, which can be caused by various substances, including heterogeneous serum (such as tetanus antitoxin), certain animal proteins (such as eggs, fish, shrimp, crab, etc.), bacteria, viruses, animal fur, Plant pollen and dust in the air, as well as paints, dyes, chemicals, plastics, chemical fibers and drugs, etc., these substances are called allergens. Allergens can stimulate human B cells to produce a substance called immunoglobulin E (IgE) in medicine, which binds to the Fc receptors of the body's own mast cells and basophils in the serum to become sensitized cells. Mast cells are mainly distributed around the skin, mucous membranes and capillaries. Once people are exposed to this allergen again, the allergen will bind to the antibody on the s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/23A61P37/08
Inventor 李云森陈子珺玄振玉陈麟刘继勇
Owner 苏州玉森新药开发有限公司
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