Chinese medicine immune regulator and its preparation and use in pharmacy

An immunomodulator, a technology of traditional Chinese medicine, applied in the field of medical drugs, can solve the problems of unsatisfactory treatment effect of middle and advanced tumors, aggravate patients' pain and restrictions, achieve the effect of inhibiting spontaneous lung metastasis and enhancing humoral immunity

Inactive Publication Date: 2003-06-18
TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although surgical treatment has achieved certain results in the treatment of some early tumors, the treatment effect on advanced tumors is not ideal, and some tumors in special parts that are not convenient for surgery restrict the operation
Although chemotherapy drugs have a certain anti-tumor effect, they have severe side effects, which often aggravate the pain of patients and even have to be stopped

Method used

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  • Chinese medicine immune regulator and its preparation and use in pharmacy
  • Chinese medicine immune regulator and its preparation and use in pharmacy
  • Chinese medicine immune regulator and its preparation and use in pharmacy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0110] (1) Mix 1200 grams of Astragalus membranaceus and 1200 grams of Acanthopanax, add water and decoct 2 times, add 12 times the amount of raw materials for the first time, decoct for 2 hours, add 6 times the amount of raw materials for the second time, decoct for 1 hours, combined the decoction, mixed evenly, left to stand for 24 hours, filtered, the filtrate was concentrated to a clear paste with a relative density (at 80°C) of 1.20, and allowed to cool to room temperature;

[0111] (2) Add ethanol to the clear paste under stirring to make the alcohol content 80%, leave it to stand for 24 hours after stirring, filter, add 900 ml of hot water to dissolve the filtered precipitate, centrifuge, filter, and add the filtrate under stirring Make the content of ethanol reach 50%, let it stand for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell;

[0112] (3) Various excipients are added, processed, and made into oral...

Embodiment 2

[0114] (1) Mix 1200 grams of Astragalus membranaceus and 1200 grams of Acanthopanax, add water and decoct 2 times, add 12 times the amount of raw materials for the first time, decoct for 2 hours, add 6 times the amount of raw materials for the second time, decoct for 1 hours, combined the decoction, mixed evenly, left to stand for 24 hours, filtered, the filtrate was concentrated to a clear paste with a relative density (at 80°C) of 1.20, and allowed to cool to room temperature;

[0115] (2) Add ethanol to the clear paste under stirring to make the alcohol content 80%, leave it to stand for 24 hours after stirring, filter, add 900 ml of hot water to dissolve the filtered precipitate, centrifuge, filter, and add the filtrate under stirring Make the content of ethanol up to 30%, let it stand for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell;

[0116] (3) Various excipients are added, processed, and made into oral...

Embodiment 3

[0118] (1) Mix 1,200 grams of astragalus and 1,200 grams of Acanthopanax, add water and decoct twice, add 8 times the amount of raw materials for the first time, decoct for 2 hours, add 4 times the amount of raw materials for the second time, and decoct for 1 hour hours, combined the decoction, mixed evenly, left to stand for 24 hours, filtered, the filtrate was concentrated to a clear paste with a relative density (at 80°C) of 1.14, and allowed to cool to room temperature;

[0119] (2) Add ethanol to the clear paste under stirring to make the alcohol content 80%, leave it to stand for 12 hours after stirring, filter, add 900 ml of hot water to dissolve the filtered precipitate, centrifuge, filter, and add the filtrate under stirring Make the content of ethanol reach 50%, let it stand for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell;

[0120] (3) Various excipients are added, processed, and made into oral liqu...

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PUM

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Abstract

A Chinese medicine as an immune regulator used for preparing the antineoplastic Chinese medicine is prepared from astragalus root and acanthopanax bark through decocting, concentrating, depositing inalcohol, and extracting from its deposit by alcohol. Its advnatage is high effect on improving immunity and playing its synergistic role in chemicotherapy and radiotherapy.

Description

technical field [0001] The invention relates to medical drugs, in particular to a traditional Chinese medicine immunomodulator and a preparation method thereof, and an antitumor medicine and a preparation method using the traditional Chinese medicine immunomodulator as an active ingredient. Background technique [0002] So far, malignant tumors are common and frequently-occurring diseases that seriously threaten human health. At present, there is no particularly effective drug for the clinical treatment of tumors. Although surgical treatment has achieved certain results in the treatment of some early tumors, the therapeutic effect on advanced tumors is not ideal, and some tumors in special parts that are not convenient for surgery restrict the operation. Although chemotherapy drugs have a certain anti-tumor effect, they have severe side effects, which often aggravate the suffering of patients and even have to be stopped. Therefore, finding antit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P35/00A61P37/02
Inventor 马宝瑕杜光张锐
Owner TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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