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Medicine for resolving sputum and relieving asthma and cough, preparing process thereof

A technology for relieving cough and asthma, and a preparation process, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve the problems of slow effect, large side effects, and unsatisfactory effects, and achieves rapid onset of effect and small dosage. , the effect of color stability

Active Publication Date: 2004-04-21
JIANGSU SIMCERE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although there are many treatment methods for cough and asthma, none of them are ideal. Most of them are treated with cough relieving, asthma relieving, and phlegm resolving, and generally Western medicine is the main treatment, and it has a single effect, such as codeine phosphate for relieving cough and theophylline for relieving asthma. , ammonium chloride to reduce phlegm, etc., but these drugs have large side effects, slow effect, and easy recurrence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1: This example is the best example

[0051]Ingredients formula: ephedra 1340g, gypsum 670g, bitter almond 1330g, platycodon 670g, scented 670g, poppy shell 670g, licorice 1330g. Prepare 1000ml.

[0052] Preparation process: according to the raw material formula, take gypsum powder and decoct in water for 1 hour, filter, and reserve the filtrate, add water to the remaining six herbs such as medicinal residue and ephedra, adjust the pH to 5, decoct twice for 1.5 hours each time, filter separately, and combine the filtrate And the above-mentioned spare liquid medicine; when concentrated to 50℃, the relative density is 1.14; let cool, add ethanol to 75% alcohol content, adjust the pH to 7.8, and filter; the filtrate is decompressed at 50℃ to recover ethanol; add appropriate amount of auxiliary materials , Add water to 1000ml, stand for 48 hours at 4°C, and filter; the medicinal solution is centrifuged at a high speed at 8000rpm and filtered with a 0.65μm filter membran...

Embodiment 2

[0054] Ingredients: 1206g of ephedra, 804g of gypsum, 1474g of bitter almond, 536g of platycodon, 804g of stems, 804g of poppy shell, and 1474g of licorice. Prepare 1000ml.

[0055] Preparation process: according to the raw material formula, take gypsum powder and decoct in water for 1 hour, filter, and reserve the filtrate, add water to the remaining six herbs such as medicinal residue and ephedra, adjust the pH to 5, decoct twice for 1.5 hours each time, filter separately, and combine the filtrate And the above-mentioned spare liquid medicine; the relative density when concentrated to 50℃ is 1.14; let cool, add ethanol to 75% alcohol content, adjust the pH value to 8.0; filter, the filtrate is decompressed at 50℃ to recover ethanol; add appropriate amount of auxiliary materials , Add water to 1000ml, let stand for 48 hours at 4℃, and filter; the liquid medicine is centrifuged at a high speed of 5000rpm; potting, sterilization, visual inspection, and packaging.

Embodiment 3

[0057] Ingredients: 1474g of ephedra, 536g of gypsum, 1206g of bitter almonds, 804g of platycodon, 804g of stems, 536g of poppy husk, 1206g of licorice. Prepare 1000ml.

[0058] Preparation process: according to the raw material formula, take gypsum and decoct in water for 1 hour, filter, and reserve the filtrate, add water to the remaining six herbs such as medicinal residue and ephedra, adjust the pH to 5.1, decoct twice for 1 hour each time, filter separately, combine the filtrate and The above standby filtrate; the relative density when concentrated to 50℃ is 1.14; let cool, add ethanol to 75% alcohol content, adjust the pH to 7.9, and filter; the filtrate is decompressed at 50℃ to recover ethanol; add appropriate amount of auxiliary materials, add water to 1000ml, stand for 48 hours at 2°C, and filter; the drug solution is centrifuged at 6000 rpm and filtered with a 0.65 μm filter membrane; potting, sterilization, visual inspection, and packaging.

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PUM

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Abstract

A Chinese medicine for treating cough and asthms and dispelling phlem is prepared from 7 Chinese-medicinal materials including ephedra, gpysum, bitter apricot kernel, liquorice root, etc through decocting gypsum powder, filtering to obtain its filtrate, decocting its dregs and others and filtering twice, collecting filtrate, concentrating, depositing in alcohol, regulating pH value, filtering, depositing in water, membrane filtering, and sterilizing. Its advantages are high curative effect, quickly taking its effect, and no by-effect.

Description

Technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and specifically relates to a medicine for relieving cough, relieving asthma and reducing phlegm and its preparation process. Background technique [0002] Cough and asthma are common and frequently-occurring diseases, which are mainly manifested as coughing, wheezing, and chest tightness. In severe cases, they may cause rapid heart rate and difficulty breathing. Especially the elderly and children have a high incidence. [0003] Although there are many treatment methods for cough and asthma recently, they are not ideal. Most of them use cough, asthma, and phlegm treatments. Western medicines are generally used, and they have a single effect, such as codeine phosphate for relieving cough and theophylline for relieving asthma , Ammonium chloride reduces phlegm, etc., but these drugs have large side effects, slow effects, and easy recurrence. Summary of the invention [0004] The pu...

Claims

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Application Information

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IPC IPC(8): A61K33/06A61P11/06A61P11/10A61P11/14
Inventor 周进东刘武罗兴洪吴海峰
Owner JIANGSU SIMCERE PHARMA
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