Preparation technology of supplementing kind capsule
A preparation process and capsule technology, which are applied in the field of Chinese herbal medicine preparation capsules, can solve the problems of inability to remove macromolecular impurities, large dosage, and strong hygroscopicity, and achieve the effects of good drug efficacy, small dosage and good tonic effect.
Active Publication Date: 2004-07-21
GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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Problems solved by technology
[0002] Traditional tonic Chinese herbal medicines are generally filtered with a 200-mesh sieve in the capsule preparation process, which cannot remove macromolecular impurities such as colloids, tannins, and proteins in the liquid medicine, resulting in poor efficacy and large dosage. Strong hygroscopicity
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0064] Embodiment of the present invention: take the production of 1000 grains as an example, get 467g of Ligustrum lucidum, 933g of Radix Astragali, pulverize, add water and decoct 3 times (10 times the amount of water for the first time, add 8 times the amount of water for the second and third times respectively) , 2 hours for the first time, 1 hour for the 2nd and 3rd times, combine the decoction, filter with a 200-mesh screen, and then perform ultrafiltration with a hollow fiber ultrafiltration membrane with a molecular weight cut-off of 50,000, and the filtrate is concentrated to a relative density of 1.07~ 1.09 (50°C) clear ointment, dried and made into granules, then dried, filled with 1000 capsules.
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A tonic capsule for the weak patient and the patient after operating, radiotherapy or chemicotherapy is prepared from lucid ligustrum fruit and astragalus root through decocting three times, collecting decoction, ultrafiltering, concentrating, granulating, drying and loading in capsules. Its advantages are high tonic effect and low dosage.
Description
Technical field: [0001] The invention relates to a process for preparing capsules from Chinese herbal medicines. technical background: [0002] Traditional tonic Chinese herbal medicines are generally filtered with a 200-mesh sieve in the capsule preparation process, which cannot remove macromolecular impurities such as colloids, tannins, and proteins in the liquid medicine, resulting in poor efficacy and large dosage. Humidity is strong. Invention content: [0003] The object of the present invention is to provide a method for preparing Chinese herbal medicine capsules by means of ultrafiltration, which can play the roles of separation, purification and concentration, so as to improve drug efficacy and reduce dosage. [0004] The present invention is achieved in the following way: extract Ligustrum lucidum and Radix Astragali three times, combine the extracts, and then perform ultrafiltration, concentrate the filtrate to a clear paste with a relative density of 1.07 to 1...
Claims
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Inventor 吕玉涛
Owner GUIZHOU XINBANG PHARMACEUTICAL CO LTD