Complex external medicine for treating psoriasis

A technology for topical drugs and psoriasis, which is applied in the field of compound topical drugs for the treatment of psoriasis, which can solve the problems of limited curative effect and achieve the effect of light skin irritation, improved stability, and clear targets

Inactive Publication Date: 2004-09-15
CHUGOKU IGAKU KAGAKUIN HIFUBIYOU KENKYUSHO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, such drugs are restricted by their inherent toxicity and selectivity, so the curative effect is limited, and adverse reactions are almost inevitable. The polygenic nature of the disease and drug treatment cannot solve the problem of recurrence, so that patients need long-term, repeated, and even life-long medication. medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The effective active ingredients of this embodiment adopt tazarotene 0.1% (weight percentage, the same below) and 17.21-clobetasol propionate 0.1%, and the matrix carrier adopts liquid paraffin, lanolin, emulsifier, antioxidant, ethanol , Propylene Glycol and Petrolatum.

Embodiment 2

[0014] The effective active ingredients of this embodiment are 0.025% tazarotene and 0.1% 17.21-diflurazone, and the matrix carrier is liquid paraffin, lanolin, emulsifier, antioxidant, ethanol, propylene glycol and petrolatum.

Embodiment 3

[0016] The effective active ingredients of this embodiment are 0.1% tazarotene and 0.2% betamethasone 17-valerate, and the matrix carrier is liquid paraffin, lanolin, emulsifier, antioxidant, ethanol, propylene glycol and petrolatum.

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PUM

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Abstract

The present invention relates to a compound medicine for external application for curing psoriasis. It is characterized by that in the matrix carrier of said compound medicine for external application are contained the following effective active components: (wt%) tazarotenje 0.025-0.1% and cortical hormone 0.01-0.2%. Its therapeutic effect is good, and it has no adverse reaction.

Description

Technical field: [0001] The invention relates to a medicine for external use for treating psoriasis, in particular to a compound medicine for external use for treating psoriasis. Background technique: [0002] Psoriasis is an immune inflammatory disease mediated by T cells with polygenic and polymorphic genetic background, and its pathogenesis is very complex. Activated T cells and inflammatory cells interact with keratinocyte-based skin tissue cells to form a series of manifestations and clinical subtypes in the whole body and local skin. The treatment of psoriasis has always been the focus of dermatology research at home and abroad. Difficulties and hotspots. [0003] The current status of psoriasis drug treatment and the therapeutic effects of existing drugs can only target a part of the complex pathogenesis of psoriasis. The development of new drugs and new preparations and the efforts of clinical therapeutics have long been without qualitative breakthroughs. Adjustmen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K31/56A61K31/57A61K38/35A61P17/06
Inventor 郑家润张崇璞李新宇陈沄高纪伟唐美育徐兰芳
Owner CHUGOKU IGAKU KAGAKUIN HIFUBIYOU KENKYUSHO
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