Biodegradable hydrogel and method for preparing same

Abstract

The invention discloses a biodegradable hydrogel and method for preparing same which consists of, preparing microporous konjak gluglucosan aqueous gel, preparing refined konjaku flour, dissolving in distilled water, agitating, charging inorganic solvent, adjusting pH, carrying out crossbridging under a controlled temperature and time, water scrubbing the product yield, repeated frost thawing, freeze-drying, then swelling the konjak gluglucosan gel into the aqueous solution of acroleic acid, cross linking agent, and initiating agent, carrying out polymerization under a controlled temperature and time, and water scrubbing the obtained outcome yield.

Description

technical field [0001] The present invention relates to the field of biomedical polymer materials, more specifically to a biodegradable hydrogel, and also to a preparation method of the biodegradable hydrogel, which is composed of konjac glucomannan hot-alkali cross-linked, freeze-thawed Process the resulting gel with an interpenetrating polymer network composed of polyacrylic acid. Background technique [0002] Polymer hydrogel is a body-shaped network of hydrophilic polymers that can swell in water and retain a large amount of water without dissolving. The many uses of hydrogels in the fields of biochemistry, medicine, agriculture, and daily chemical industry have aroused the general attention of scientists. Polyacrylic acid hydrogel is a widely used synthetic polymer material with pH responsiveness, and has a good application prospect in oral pharmaceutical preparations. However, its non-biodegradability limits its application in biomedicine. ...

AI Technical Summary

Problems solved by technology

So far, there is no report on the preparation of konjac glucomannan / polyacrylic acid hydrogel by interpenetrating polymer network technology