Apoplexy treating medicine composition

A composition and drug technology, applied in the direction of drug combination, drug delivery, active ingredients of hydroxyl compounds, etc., to achieve the effect of improving Qi deficiency and blood stasis symptoms with definite curative effect

Active Publication Date: 2006-08-02
YUNNAN BIOVALLEY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Now there are many therapeutic drugs used to treat stroke, such as: Naoshuan Kangfu Capsules, Cerebral Thrombosis Tablets, etc. In clinical application, these drugs can treat both cerebral hemorrhage and cerebral stasis, but these drugs are not specially used to treat the late stage of stroke (recovery period), so far there is no medicine specifically for the treatment of stroke late stage (convalescence period), so the market is in urgent need of developing a medicine for the treatment of cerebral apoplexy in the recovery period. The purpose of its treatment is to promote the recovery of function, reduce sequelae, and improve ability to work and quality of life, and to prevent relapse

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Embodiment 1 capsule

[0074] Prescription: Erigeron 1089 parts, Danshen 653 parts, Astragalus 653 parts, borneol 5 parts

[0075] Preparation:

[0076] Take breviscapine and add 60% ethanol to reflux extraction twice, each time for 2 hours, combine the extracts, concentrate under reduced pressure and recover ethanol until the relative density of the concentrated solution is 1.13 (45°C), adjust the pH to 6-7 with 10% sodium hydroxide solution, Stand still for 24 hours, filter, adjust the pH of the filtrate to 2-3 with dilute sulfuric acid test solution, let stand for 48 hours, filter, wash the precipitate with water twice, set aside, and set aside the filtrate;

[0077] Take red ginseng and decoct in water twice, 2 hours each time, combine the liquid medicines, concentrate under reduced pressure to a clear paste with a relative density of 1.07-1.10 (65°C), place it at room temperature, add ethanol under stirring, and make the ethanol content ...

Embodiment 2

[0079] Embodiment 2 soft capsules

[0080] Prescription: Erigeron breviscapus 1390 parts, Salvia miltiorrhiza 453 parts, Astragalus membranaceus 549 parts, borneol 8 parts

[0081] Preparation method: the preparation of the composition is the same as in Example 1;

[0082] According to the preparation method of conventional soft capsules, soft capsules are made. After testing, the capsules contain 5.68mg / capsule of scutellarin.

Embodiment 3

[0083] Example 3 tablet

[0084] Prescription: Erigeron 1089 parts, Danshen 500 parts, Astragalus 653 parts, borneol 5 parts

[0085] Preparation method: the preparation of the composition is the same as in Example 1;

[0086] According to the preparation method of conventional tablet, make tablet. After testing, it contains scutellarin 5.20mg / tablet.

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PUM

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Abstract

The present invention relates to one kind of medicine composition and its preparation and application. The medicine composition consists of Chinese medicinal materials or their extracts, including shortscape fleabane herb, 14-29 weight portions, red sage 1-17 weight portions, astragalus root 8-17 weight portions and borneol 0.06-0.13 weight portions. The medicine composition is used for treating apoplexy.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a traditional Chinese medicine composition for treating apoplexy. Background technique [0002] Stroke is the name of traditional Chinese medicine for cerebrovascular accident-type diseases. It is a common and frequently-occurring disease caused by abnormalities of vascular factors, blood factors and blood flow factors. It is characterized by rapid onset, speech impairment, disturbance of consciousness, crooked mouth and eyes, and hemiplegia. Its morbidity, mortality and disability rates are quite high, and about 60-80% of survivors after stroke have disabilities of varying degrees, which seriously affects their quality of life and causes significant economic and mental burdens to society and families . [0003] More than 85% of the stroke-disabled population is over 50 years old, and the proportion increases with age. Most of these patients suffer from insufficient righteousne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P9/10A61K31/045
Inventor 潘锡平
Owner YUNNAN BIOVALLEY PHARMA CO LTD
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