Saussurea and coptis preparation and preparation method

A technology of preparation and traditional Chinese medicine preparation, which is applied in the direction of pill delivery, medical formula, and resistance to vector-borne diseases, etc. It can solve the problems of many impurities, affecting clinical application, and large doses.

Inactive Publication Date: 2006-08-30
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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  • Saussurea and coptis preparation and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] The preparation method of dropping pill of the present invention:

[0063] prescription:

[0064] Coptis chinensis (made by Evodia rutaecarpa) 480g Woody fragrance 120g

[0065] PEG4000 100g

[0066] Makes 1000 pills

[0067] Preparation:

[0068] (1) Get the woody medicinal material and use steam distillation (or supercritical extraction method): chop the medicinal material and extract it according to the 2005 Pharmacopoeia Part I Appendix XD volatile oil extraction method until the height of the volatile oil does not increase any more; β- For CD inclusion, the best process is: the ratio of β-CD to water is 1:8, the ratio of oil to β-CD is 1:8, sonication for 30-70 minutes to obtain the inclusion compound; the obtained water extract is filtered and concentrated into a thick Extract, spare;

[0069] (2) Take Coptis rhizome powder, extract it twice with 1% (v / v) sulfuric acid cold soaking, 24 hours each time, filter, add calcium hydroxide fine powder to the filtrate...

Embodiment 2

[0072] The preparation method of soft capsule of the present invention:

[0073] prescription:

[0074] Coptis chinensis (made by Evodia rutaecarpa) 2400g Woody fragrance 600g

[0075] PEG400500g

[0076] Makes 1000 capsules

[0077] Preparation:

[0078] (1) Get the woody medicinal material and use steam distillation (or supercritical extraction method): chop the medicinal material and extract it according to the 2005 Pharmacopoeia Part I Appendix XD volatile oil extraction method until the height of the volatile oil does not increase any more; β- For CD inclusion, the best process is: the ratio of β-CD to water is 1:8, the ratio of oil to β-CD is 1:8, sonication for 30-70 minutes to obtain the inclusion compound; the obtained water extract is filtered and concentrated into a thick Extract, spare;

[0079] (2) Take Coptis rhizome powder, extract it twice with 1% (v / v) sulfuric acid cold soaking, 24 hours each time, filter, add calcium hydroxide fine powder to the filtrat...

Embodiment 3

[0082] The preparation method of granule of the present invention:

[0083] prescription:

[0084] Coptis chinensis (made by Evodia rutaecarpa) 2000g Woody fragrance 500g

[0085] Made into 1000g

[0086] Preparation:

[0087] (1) get the woody medicinal material and grind it into medicine;

[0088] (2) Take Coptidis medicinal material, percolate with 0.1% hydrochloric acid ethanol (95%) solution, collect the acidic ethanol extract, recover ethanol under reduced pressure, and obtain the concentrate;

[0089] (3) Combine the above active ingredients, add 5.0 g of aspartame and 260.0 g of dextrin, granulate, dry, and spray 5.0 g of essence to obtain 1000 g of granules.

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PUM

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Abstract

A composite Chinese medicine in the form of dripping pill and soft capsule for treating damp-heat dysentery, tenesmus diarrhea, bacterial dysentery and enteritis, and its preparing process are disclosed.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription for damp-heat dysentery, tenesmus, abdominal pain and diarrhea; bacillary dysentery and enteritis and the preparation process thereof. Background technique: [0002] Damp-heat dysentery, tenesmus, abdominal pain and diarrhea; bacillary dysentery and enteritis are common clinical symptoms. Traditional Chinese medicine often treats them by clearing away heat and dampness, promoting qi and relieving pain, and the curative effect is remarkable. Xianglian Wan is its representative drug. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction process of the present invention can better collect the essence of the m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/48A61K9/20A61K9/16A61P1/00A61P1/12
CPCY02A50/30
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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