Bilobalide B emulsion for injection
A technology for ginkgolide and injection, which is applied in the field of ginkgolide B emulsion, which can solve the problems of large irritation of organic solvents, improve safety and effectiveness, improve curative effect, increase orientation and harmonize cancer cells Effect
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Embodiment 1
[0036] Dissolve 22.5g of glycerin in water for injection, 2.0g of ginkgolide B and 12.0g of refined soybean lecithin in refined soybean oil, respectively heat to 50°C, mix well, first emulsify fractionally in a tissue masher, and then Emulsified by a high-speed homogenizer to meet the particle size of the preparation. Add water for injection to 1000ml, cool, and fill to obtain ginkgolide B injection emulsion. This process is a 1000ml prescription, and the production can be expanded, and nitrogen protection is required during the production process.
Embodiment 2
[0038] Dissolve 25.0 g of sorbitol in water for injection, 5.0 g of ginkgolide B and 10 g of refined lecithin in refined corn oil, respectively heat to 45°C, mix well, first fractionally emulsify in a tissue masher, and then The high-speed homogenizer emulsifies to meet the particle size of the preparation. Add water for injection to 1000ml.
Embodiment 3
[0040] Dissolve 55.5g of xylitol in water for injection, 10.0g of ginkgolide B and 15.0g of refined lecithin in refined sesame oil, heat to 60°C respectively, mix well, first emulsify fractionally in a tissue masher, and then Emulsified by a high-speed homogenizer to meet the particle size of the preparation. Add water for injection to 1000ml.
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