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Composition of Chinese traditional medicine for treating phthisis, and application

A tuberculosis and composition technology, applied in the field of traditional Chinese medicine composition for the treatment of tuberculosis, can solve the problems of tuberculosis sensitivity decline, side effects, and long-term change of lesions

Active Publication Date: 2010-12-22
SHENYANG HONGQI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above several western medicines are generally used in combination in the treatment of pulmonary tuberculosis. Although they also have certain therapeutic effects, their toxic and side effects will bring new diseases and misery to patients.
Chemotherapy can alleviate the condition to a certain extent. The initial treatment can excrete 95-100% of bacteria, and the sputum bacteria can be turned negative. However, chemotherapy has certain side effects on the liver, kidney, and gastrointestinal functions of patients, which makes many patients unable to adhere to medication. , long-term irregular medication, resulting in drug resistance of Mycobacterium tuberculosis, an increase in drug-resistant cases and long-term changes in lesions, causing great pain to patients. Therefore, due to the increasing variation of tuberculosis strains and drug resistance
As a result, the effect of the original anti-tuberculosis drugs is obviously not as good as before, and some anti-tuberculosis drugs with better efficacy, such as rifampicin, isoniazid, streptomycin, etc., are significantly less sensitive to Mycobacterium tuberculosis, and have relatively large toxic and side effects; And the patient is difficult to accept long-term chemical treatment, so tuberculosis quietly breeds again, turbulent resurgence, once again threatens the health of human beings

Method used

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  • Composition of Chinese traditional medicine for treating phthisis, and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation method of the syrup of the present invention:

[0021] Weigh each raw material: 450 grams of Humulus, 450 grams of dandelion, 400 grams of Polygonum multiflorum, 400 grams of Stemona, 250 grams of Bletilla striata, and 250 grams of Polygonatum, decoct twice in water for 1 hour each time, filter, combine the filtrate, and concentrate into a thick paste , Precipitate twice with ethanol to make the alcohol content reach 65% for the first time, 80% for the second time, filter, recover the ethanol and concentrate to about 700mL, add sucrose and ethylparaben alcohol solution while stirring to dissolve , Add boiling water to the full amount, stir evenly to get.

Embodiment 2

[0023] The preparation method of the granule of the present invention:

[0024] Weigh 500 grams of Humulus humulus, 050 grams of dandelion, 500 grams of Polygonum multiflorum, 300 grams of Baibu, 3000 grams of Bletilla striata, and 300 grams of Polygonatum. The above-mentioned drugs were crushed and crushed into coarse powder, decocted twice, the first time was 2 hours, the second time was 1 hour, filtered, the filtrate was concentrated into a thick paste, dried, crushed through a 100-mesh sieve, mixed, moistened, softened, and formed Take it out when clumping and make granules.

Embodiment 3

[0026] (a) Perform reflux extraction twice with 70%-95% ethanol of Humulus, dandelion and Polygonum multiflorum in the said weight ratio, combine the two extracts, recover the ethanol, and dry at 45-55°C to obtain dry leaching Cream 1

[0027] (b) The residue after alcohol extraction of Polygonatum, Bletilla striata, Stemone and Humulus, Dandelion, and Polygonum multiflorum in the stated weight ratio is decocted twice with water, each time adding water to make the medicinal noodles easy, and the two decoctions are combined , Filtrate to obtain filtrate 2, concentrate the filtrate into an extract with a specific gravity of 1.15 to 1.35, and dry it at 45 to 55°C to obtain dry extract 2;

[0028] (c) Combine dry extract 1 and 2 and pulverize them into powder to prepare the active ingredient of the drug of the invention;

[0029] (d) Fully mix the obtained active ingredients with pharmaceutically acceptable additives such as correctives and excipients to prepare any pharmaceutical dosag...

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Abstract

A Chinese medicine in the form of particle or others for treating pulmonary tuberculosis is prepared from 6 Chinese-medicinal materials including dandelion herb, fleece flower root, stemona root, bletilla tuber, etc. Its preparing process is also disclosed.

Description

Technical field [0001] The invention relates to a Chinese patent medicine, in particular to a Chinese medicine composition for treating pulmonary tuberculosis with Chinese medicine as the main component and its application. Background technique [0002] Pulmonary tuberculosis is a common intractable disease, and a more common chronic infectious disease caused by tuberculosis infection. Tuberculosis can occur in various tissues and organs of the human body, but the lungs are the most common. Tuberculosis that occurs in the lungs is called tuberculosis. The treatment of tuberculosis at home and abroad generally uses western medicine and chemotherapy. Modern Western medicine for the treatment of tuberculosis is mainly isoniazid: its main toxic and side effects are irritability, insomnia, peripheral diabetic inflammation, and occasional liver damage; rifampicin: its main side effects are liver damage, thrombocytopenia, pregnancy Early women are prone to teratogenesis; pyrazinamide:...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K9/48A61K36/904A61P31/06A61K9/00A61K9/20
Inventor 杨熠锴
Owner SHENYANG HONGQI PHARMA
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