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Herb medicine composition contg. Touhualiao (polygonaceae), prepn. method and use thereof

A composition and technology of Polygonum cephalus, which are applied in the field of medicine to achieve the effects of shortening bleeding time, improving dilation state and promoting metabolic function

Inactive Publication Date: 2007-04-18
海安江理工技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, using the interaction of Polygonum cephalosporin or its extracts, Imperata rhizome or its extracts, thistle or its extracts for the preparation of medicines for treating genitourinary system diseases, there is no report yet

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0154] Example 1 Preparation and Content Determination of Polygonum cephalum Extract

[0155] Preparation of Polygonum cephalica Extract

[0156] Take 10kg Polygonum cephalum, chop it, add water and decoct twice, 2 hours each time, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.10-1.15, let it cool, add ethanol to make the alcohol content to 60% , refrigerated for 24 hours, filtered, recovered ethanol from the filtrate until almost no alcohol smell, added to the treated polyamide column (1000g, 30-60 mesh, column inner diameter 3mm, wet-packed with ethanol, pre-washed with appropriate amount of ethanol, and then used Wash with water until there is no alcohol smell, and then wash with 2 times the column volume of water, then wash with 2 times the column volume of 10% ethanol, discard the washing solution, and then use 3 times the column volume for elution with 70% ethanol, The eluent is collected, ethanol is recove...

Embodiment 2

[0165] Example 2 Preparation and Content Determination of Imperata Rhizome Extract

[0166] Preparation of Imperata Rhizome Extract

[0167] Take 10kg of Imperatae Rhizome, add water and reflux to extract twice, each extraction for 2 hours, add 10 times the amount of water, combine the extracts, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.15-1.20, pass through the treated macroporous resin column, Wash the column with 2 times the amount of water first, then elute with 60% ethanol, collect the eluate, recover the ethanol under reduced pressure, concentrate, and dry in vacuo to obtain the product.

[0168] Three batches of Imperata rhizome extracts were prepared respectively, and the yields are shown in Table 2-2.

[0169] Content Determination of Imperata Rhizome Extract

[0170] Determination of the content of total phenolic substances

[0171] Determination method is the same as "the content determination of total flavonoids" in E...

Embodiment 3

[0174] Example 3 Preparation and content determination of thistle extract

[0175] Preparation of thistle extract

[0176] Get 10kg of Imperatae Rhizome, add 75% ethanol to heat and reflux twice, extract 2 hours each time, add 8 times the amount of alcohol, combine the extracts, filter, and the filtrate reclaims ethanol and concentrates to an appropriate amount (equivalent to 1 / 2 of the amount of medicinal material). ), add the same amount of petroleum ether and shake and extract 3 times, discard the petroleum ether liquid, evaporate the petroleum ether with water, add it to the treated polyamide column (14-30 mesh, ethanol wet packing, first use ethanol Wash, and then rinse with water until there is no alcohol smell, set aside), first rinse with 2 times the amount of water, then rinse with 2 times the amount of 10% ethanol, and finally elute with 95% ethanol, collect the eluate, recover the ethanol and decompress Concentrate, dry in vacuum, and crush to get it.

[0177] Thr...

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PUM

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Abstract

A composite Chinese medicine in the form of orally taken medicine and injection for treating the diseases in urinary system and reproductive system is proportionally prepared from Touhua knotweed or its extract, imperate rhizome or its extract, and optional cephalanoplos herb or its extract. Its preparing process is also disclosed.

Description

1. Technical field [0001] The invention relates to a Polygonum cephalosporin compound medicinal composition and a preparation method thereof, its application in the preparation of medicines for treating urogenital diseases and a preparation containing the medicinal composition, belonging to the technical field of medicine. 2. Background technology [0002] Urogenital system diseases are common diseases, which pose a serious threat to people's physical and mental health. At present, there are many drugs for the treatment of urogenital diseases, but most of them are expensive, take a long time to treat, and have poor therapeutic effects. At present, traditional Chinese medicine or Western medicine methods are commonly used to treat common genitourinary system diseases. Traditional Chinese medicine is based on the basic principle of clearing the benefit and eliminating evil for the excess, and tonifying the kidney and strengthening the body for the deficient. If it is damp-he...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P13/00A61P15/00
Inventor 黄振华
Owner 海安江理工技术转移中心有限公司
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