Column type extraction device for pipe bundle multi-channel phase-dispersing and extraction method thereof

Abstract

The invention relates to a column type extraction device for pipe bundle multi-channel phase-dispersing; a main shaft is arranged inside the column type extraction device; two or at least three hollow thin tubes in parallel to the main shaft are distributed on the outer circumference of the main shaft; one end of each hollow thin tube is provided with a straight tube, and the other end of the hollow thin tube is bent to form a flanged bend; the bending direction of the flanged bend is the remote direction of a mounting shaft; the main shaft is connected with an electric motor, and drives the hollow thin tubes to carry out motion at a same speed with the main shaft when the main shaft rotates. The column type extraction device disclosed by the invention solves the difficult problems that a water phase or an oil phase with relatively small volume is difficult to disperse completely in the conventional mechanical stirring manner when the volume ratio of the water phase to the oil phase in an extraction process is large; and the difficult problems that the water phase and the oil phase are difficult to clarify and separate in an extraction system and the like caused by easy emulsification are also solved when the flow-rate ratio of the water phase to the oil phase is large.

Description

technical field

[0001] The invention belongs to the technical field of extraction in chemical separation, and relates to an extraction device and an extraction method. Specifically, the invention relates to a tube-bundle multi-channel phase-dispersed column extraction device and extraction. Background technique

[0002] Extraction is an efficient chemical separation technology and one of the most promising green chemical development directions in the 21st century. As an important branch of chemical separation, extraction technology can select the appropriate extraction system and process according to the separation object and process requirements. It has the characteristics of high selectivity, good separation effect, easy operation and strong adaptability, so it is widely used in wet Metallurgy, petrochemical, atomic energy chemical, pharmaceutical, environmental protection, bioengineering and new material preparation and other fields. Research and development of new extra...

Examples

Embodiment 1

[0093] The organic phase is 50mM AOT / petroleum ether (bp.:90-120°C), the aqueous phase is lysozyme containing 1mg / mL, 0.05M borax-hydrochloric acid (HCl) buffer, potassium chloride salt concentration 0.1M, pH= 9.0. The inner diameter of the cylindrical cavity of the tower body is 80mm, and the height is 100mm. The height of the cavity at both ends of the tower body is 20mm. slim tube. The water phase is used as the dispersed phase, and the structure of the device is as follows: figure 1 shown. Motor speed 600r / min. A single-stage continuous extraction operation is carried out, and the two-phase flow ratio is controlled so that the volume ratio of the organic phase and the aqueous phase in the tower is 12:1. The concentration of lysozyme in the water phase flowing out from the heavy phase outlet 15 in the lower part of the tower body was detected, and the extraction rate was 90.8%.

Embodiment 2

[0095] The organic phase is 5.7wt% tributylphosphine oxide (TBPO) in butyl acetate solution, the aqueous phase is 0.05M penicillin potassium saline solution containing 1mg / mL whey protein, pH=4.0. The structural parameters of the tower body and the liquid phase disperser are the same as in Example 1. The organic phase is used as the dispersed phase, and the structure of the device is as follows: Figure 7 shown. Motor speed 600r / min. Perform single-stage continuous extraction operation, and control the two-phase flow ratio so that the volume ratio of the organic phase and the aqueous phase in the tower is 1:20. Detect the content of penicillin in the water phase flowing out from the heavy phase outlet 15 in the lower part of the tower body, and the extraction rate is 92.5%.

Embodiment 3

[0097] The organic phase and water are the same as Example 1. The structural parameters of the tower body and the liquid phase disperser are the same as in Example 1. The light and heavy phases are dispersed at the same time, and the structure of the device is as follows Figure 8 shown. Motor speed 600r / min. The single-stage continuous extraction operation is carried out, the two phases flow countercurrently in the device, and the flow ratio of the two phases is controlled so that the volume ratio of the organic phase and the aqueous phase in the tower is 1:1. The concentration of lysozyme in the water phase flowing out from the heavy phase outlet 15 in the lower part of the tower body was detected, and the extraction rate was 96.0%.

technical field

[0001] The invention belongs to the technical field of extraction in chemical separation, and relates to an extraction device and an extraction method. Specifically, the invention relates to a tube-bundle multi-channel phase-dispersed column extraction device and extraction. Background technique

[0002] Extraction is an efficient chemical separation technology and one of the most promising green chemical development directions in the 21st century. As an important branch of chemical separation, extraction technology can select the appropriate extraction system and process according to the separation object and process requirements. It has the characteristics of high selectivity, good separation effect, easy operation and strong adaptability, so it is widely used in wet Metallurgy, petrochemical, atomic energy chemical, pharmaceutical, environmental protection, bioengineering and new material preparation and other fields. Research and development of new extra...

Examples

Embodiment 1

[0093] The organic phase is 50mM AOT / petroleum ether (bp.:90-120°C), the aqueous phase is lysozyme containing 1mg / mL, 0.05M borax-hydrochloric acid (HCl) buffer, potassium chloride salt concentration 0.1M, pH= 9.0. The inner diameter of the cylindrical cavity of the tower body is 80mm, and the height is 100mm. The height of the cavity at both ends of the tower body is 20mm. slim tube. The water phase is used as the dispersed phase, and the structure of the device is as follows: figure 1 shown. Motor speed 600r / min. A single-stage continuous extraction operation is carried out, and the two-phase flow ratio is controlled so that the volume ratio of the organic phase and the aqueous phase in the tower is 12:1. The concentration of lysozyme in the water phase flowing out from the heavy phase outlet 15 in the lower part of the tower body was detected, and the extraction rate was 90.8%.

Embodiment 2

[0095] The organic phase is 5.7wt% tributylphosphine oxide (TBPO) in butyl acetate solution, the aqueous phase is 0.05M penicillin potassium saline solution containing 1mg / mL whey protein, pH=4.0. The structural parameters of the tower body and the liquid phase disperser are the same as in Example 1. The organic phase is used as the dispersed phase, and the structure of the device is as follows: Figure 7 shown. Motor speed 600r / min. Perform single-stage continuous extraction operation, and control the two-phase flow ratio so that the volume ratio of the organic phase and the aqueous phase in the tower is 1:20. Detect the content of penicillin in the water phase flowing out from the heavy phase outlet 15 in the lower part of the tower body, and the extraction rate is 92.5%.

Embodiment 3

[0097] The organic phase and water are the same as Example 1. The structural parameters of the tower body and the liquid phase disperser are the same as in Example 1. The light and heavy phases are dispersed at the same time, and the structure of the device is as follows Figure 8 shown. Motor speed 600r / min. The single-stage continuous extraction operation is carried out, the two phases flow countercurrently in the device, and the flow ratio of the two phases is controlled so that the volume ratio of the organic phase and the aqueous phase in the tower is 1:1. The concentration of lysozyme in the water phase flowing out from the heavy phase outlet 15 in the lower part of the tower body was detected, and the extraction rate was 96.0%.

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