The invention discloses an extraction method of a
clerodendranthus spicatus total flavone extract. The method comprises the following steps: adding an
ethanol aqueous solution with a liquid-material ratio of 5-25 L / Kg and a concentration of 0-95% into a
clerodendranthus spicatus
powder, performing soaking at
room temperature for 1-48h with stirring, performing ultrasonic treatment, filtering the obtained extract liquid, and concentrating filtrate to obtain a paste; and separating the paste with weak-polar macroporous adsorbent resin columns, performing
elution with 2-4BV water to remove impurities, performing
elution with 2-4BV
ethanol with a concentration of 0-95%, collecting
ethanol eluent, recovering ethanol under reduced pressure, and performing
drying under reduced pressure to obtaintotal flavone extract. The experimental results show that the total flavone extract of the
kidney tea can promote serum
creatinine and
urea nitrogen levels of mice to be obviously reduced, the calciumcontent of
kidney tissues to be obviously reduced, and the
crystal deposition of
calcium oxalate in
kidney tissues and the
pathological tissue injury of the kidney to be obviously reduced. The
clerodendranthus spicatus total flavone extract has effect in preventing or treating
urinary calculus, and can be used for preparing medicines, health products or foods for preventing or treating
urinary calculus.