The invention relates to the field of sewage treatment, and particularly discloses a composite water quality agglutination purifying agent and a preparation method thereof. The composite water quality agglutination purifying agent is prepared from the following components in parts by weight: 550 to 600 parts of calcined silica, 30 to 70 parts of rare earth porcelain sand, 20 to 65 parts of white mica, 90 to 120 parts of polyaluminum chloride, 15 to 50 parts of serpentine and 15 to 45 parts of polyacrylamide. The preparation method comprises the following steps: respectively crushing the muscovite, the serpentine and the rare earth porcelain sand, mixing, adding water accounting for 10-15% of the total weight of the muscovite, the serpentine and the rare earth porcelain sand, carrying out ball milling, drying and sieving, adding the calcined silica, the polyacrylamide and the polyaluminum chloride, and uniformly mixing. The composite water quality agglutination purifying agent has the advantages of being not affected by water temperature, suitable for both hot areas and severe cold areas, wide in applicable water quality range, high in removal rate of COD, TN, TP and the like, and capable of achieving the immediate and long-acting removal effect on algae.