Preparation method of magnetic guiding anticancer medicine

A technology of magnetic guidance and medicament, applied in the medical field, can solve the problems of small adsorption capacity, small adsorption capacity, difficult drug storage, etc.

Inactive Publication Date: 2008-04-30
DEZHOU KELONG CARRIER INST
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Problems solved by technology

These magnetic carriers all have the following disadvantages: very large particle or capsule size, very low magnetism, small adsorption capacity, it is difficult to form drug accumulation in the tumor area, and it is difficult to prepare, store and apply the preparation
Such particles have only a small adsorption capacity and are contaminated with pyrolysis products, making them unsuitable for medical use

Method used

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  • Preparation method of magnetic guiding anticancer medicine

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Embodiment Construction

[0008] Reduced iron powder with a particle size of 10-100 microns and activated carbon powder with a particle size of 10-1000 microns are used as raw components. These powders were mixed and ground against each other in a ball mill for 4 hours. The weight fraction of iron in the mixture is in the range of 40-70%. This share is determined by the lower recondensation conditions and the loss of various components in the centrifugal separator of the plasma generator. The weight fraction of iron in the binder obtained after recoagulation is in the range of 40-50%.

[0009] Recondensation (evaporation followed by condensation) of the mixture was achieved in a nitrogen plasma medium of a direct current plasma generator. The mixture was fed into the arc discharge zone with a stream of nitrogen. The current of the arc is 50-200 amps and the arc voltage is 200 volts. The temperature of the arc discharge is about 6000°C. The components of the mixture evaporate in the arc. After the...

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Abstract

A magnetically pilotted anticancer medicine is prepared by adding the magnetic Fe-C attachment to the medium containing the blood plasma substitute and anticancer medicine. Under the monitor of angiography, said medicine can be pilotted magnetically in the blood supplying artery of tumor to form thrombus in the blood vessels around the tumor, so fully playing the role of anticancer medicine.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a method for preparing magnetically controlled medicaments in oncology. Background technique [0002] The treatment method for treating tumors by magnetically controlled delivery of anti-tumor preparations can protect the heart, liver, bone marrow and other important tissues from damage. Several approaches are known to achieve magnetically guided anticancer agents in modern times. All of these approaches use drugs bound to ferromagnetic particles. These magnetic carriers all have the following disadvantages: very large particle or capsule size, very low magnetism, small adsorption capacity, it is difficult to form drug accumulation in the tumor area, and the formulation is difficult to prepare, store and apply. The closest to our proposed method is the NO.1722256 Soviet patent, the patent application number is SU4767768, and the date of application was November 2, 1989. In this patent, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/02B22F9/14A61K9/00A61K9/19A61K41/00A61P35/00
Inventor 阿那多列秦吉升任长春邢继红岳建强
Owner DEZHOU KELONG CARRIER INST
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