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Medicinal composition for treating high blood pressure

A composition and high blood pressure technology, applied in the direction of drug combination, pharmaceutical formula, cardiovascular system diseases, etc., can solve the problems of many complications, low cure rate, and few side effects

Inactive Publication Date: 2008-05-28
苏金平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are the following problems: first, the main pathogenic factors of most diseases are unknown; second, most diseases have more complications; third, even if the etiology is known, it is almost impossible for a chemical component to inhibit all causes
However, as hypertension is a disease with uncertain etiology, the cure rate of drugs targeting one or more effects of one etiology or mechanism of action is relatively low. Usually, the cure rate of one drug is about 40-50%, and poor prognosis
In recent years, although there are many new antihypertensive drugs with good curative effect and few side effects, the blood pressure control rate can only reach 50-60%

Method used

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  • Medicinal composition for treating high blood pressure
  • Medicinal composition for treating high blood pressure
  • Medicinal composition for treating high blood pressure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Nifedipine 5.0mg, calcium citrate 1000mg, starch 180mg, sucrose 15mg.

Embodiment 2

[0057] Nitrendipine 5.0mg, calcium gluconate 2000mg, starch 380mg, dextrin 15mg.

Embodiment 3

[0059] Prazosin 0.5mg, calcium gluconate 2000mg, corn starch 380mg, dextrin 19.5mg.

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PUM

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Abstract

A composite medicine for treating hypertension contains proportionally one or two antihypertensive medicines chosen from calcium antagon, alpha receptor blocker, beta receptor blocker, renin-angiotonin system regulator and diuretic, one Ca containing component and the farmacologically acceptable auxiliary.

Description

technical field [0001] The present invention relates to a pharmaceutical composition, more specifically, the present invention relates to a pharmaceutical composition for treating hypertension. Background technique [0002] Hypertension is one of the most common cardiovascular diseases with increased systemic arterial pressure as the main clinical manifestation, often accompanied by stroke, myocardial infarction, heart failure, coronary heart disease, diabetes and other complications. According to the guidelines for the treatment of hypertension in my country, adults over the age of 18 have systolic blood pressure greater than or equal to 140mmHg and (or) diastolic blood pressure greater than or equal to 90mmHg is hypertension. A large number of studies have shown that increased systolic blood pressure is more harmful than increased diastolic blood pressure. [0003] Surveys show that the prevalence of hypertension among adults in my country is 18.8%. It is estimated that t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K45/06A61K33/06A61K9/20A61K9/48A61P9/12A61K31/4422A61K47/02
CPCA61K47/02A61K33/06A61K31/4422A61K45/06A61P9/12A61K2300/00
Inventor 彭继道刘丽笙苏金平杨家秀
Owner 苏金平
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