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Pharmaceutical preparation with functions of clearing heat, removing dampness and benefiting gallbladder

A pharmaceutical preparation and functional technology, applied in the field of medicine, can solve the problems of long disintegration time limit, large amount of excipients, low bioavailability, etc., and achieve the effect of facilitating human body absorption and increasing stability

Active Publication Date: 2008-10-22
GUANGDONG LUOFUSHAN SINOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the tablet formulation has a large amount of auxiliary materials, low bioavailability, long disintegration time limit, etc., and is not suitable for the modern development trend of traditional Chinese medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1: Preparation of a drug extract with functions of clearing heat, removing dampness and promoting choleresis:

[0067] 1 part of Andrographis paniculata, 1 part of Xihuangcao, 1 part of Bitterwood

[0068] Andrographis paniculata and bitter wood were heated and extracted twice with 50% ethanol, filtered; Xihuangcao was decocted twice with 13 times of water, each decocting for 1.5 hours, the decoction was combined, filtered, and the decoction was concentrated to 1.20 (50 ℃ ), add five times the amount of 60% ethanol, stir evenly, stand still, and filter; the above two alcohol solutions are respectively recovered ethanol, concentrated to obtain a thick paste, or dried, and pulverized into fine powder to obtain a dry paste. The dry or thick paste is the medicinal material extract; or it can be dried and crushed into fine powder.

Embodiment 2

[0069] Embodiment 2: Preparation of a medicinal extract with functions of clearing away heat, removing dampness and promoting choleresis:

[0070] 2 parts of Andrographis paniculata, 2 parts of Xihuangcao, 2 parts of Bitterwood

[0071] Andrographis paniculata and bitter wood were heated and extracted twice with 95% ethanol, and filtered; Xihuangcao was decocted twice with 12 times the amount of water, each time for 1 hour, and the decoction was combined, filtered, and the decoction was concentrated to a relative density of 1.30 (50 ℃), add five times the amount of 75% ethanol, stir well, let stand, and filter; recover the ethanol from the above two alcohol solutions respectively, concentrate to obtain a thick paste, or dry and pulverize into fine powder to obtain a dry paste. The obtained dry paste or thick paste is the medicinal material extract; or it can be further dried and crushed into fine powder.

Embodiment 3

[0072] Example 3: Preparation of a drug extract with functions of clearing heat, removing dampness and promoting choleresis:

[0073] 1.5 parts of Andrographis paniculata, 1.5 parts of Xihuangcao, 1.5 parts of Bitterwood

[0074] Andrographis paniculata and bitter wood were heated and extracted twice with 82.5% ethanol, filtered; Xihuangcao was decocted twice with 15 times the amount of water, each time for 1 hour, the decoction was combined, filtered, and the decoction was concentrated to 1.35 (50°C), Add five times the amount of 95% ethanol, stir well, let it stand, and filter; recover the ethanol from the above two alcohol solutions, concentrate to obtain a thick paste, or dry and pulverize into fine powder to obtain a dry paste. Or the thick paste is the medicinal material extract; or it can be dried and crushed into fine powder.

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Abstract

Disclosed is a pharmaceutical preparation with functions of clearing heat, removing dampness and benefiting gallbladder, wherein the preparation has the advantages of quick release rate, high biological availability, accurate dosage, and easy administration.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicinal preparation with the functions of clearing away heat, removing dampness and promoting choleresis and a preparation method thereof. Background technique [0002] The traditional Chinese medicine Xihuangcao is a plant of the genus Lamiaceae. ex D.Don)H.Hara] dried whole herb has the functions of clearing away heat and dampness, reducing jaundice, cooling blood and dissipating blood stasis; it is used for damp-heat jaundice, damp-heat diarrhea, bruises and bruises; it is recently used for acute jaundice hepatitis , Acute cholecystitis with jaundice. [0003] The traditional Chinese medicine Picrasma quassiodes (D.Don) Ben is a plant of the genus Picrasma quassiodes. It is widely distributed and rich in resources in our country. The nature and flavor of this medicine are bitter and cold, slightly poisonous. Return lung, large intestine channel. Function and indications are an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/53A61K36/19A61K36/185A61P1/16
Inventor 叶耀良廖志钟
Owner GUANGDONG LUOFUSHAN SINOPHARM
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