Lonicera and scutellaria drip pill and preparation method thereof

The technology of Huang Dropping Pill and Baicalin is applied in the field of traditional Chinese medicine dropping pills and the preparation thereof, which can solve the problems of easy change of active ingredients and inability to make dropping pills with stable curative effect, avoids the first-pass effect of the liver, and is beneficial to labor protection. , the effect of high production efficiency

Active Publication Date: 2009-04-01
TIANJIN ZHONGTIAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] After experiments, we found that the active ingredients of honeysuckle extract are prone to change under high temperature for a long time, so the conventional method for preparing drop pills cannot be made into drop pill preparations with stable curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A Yinhuang Dropping Pill is prepared by the following method: (1) take the honeysuckle extract containing chlorogenic acid and the scutellaria baicalensis extract containing baicalin as raw materials, and make the weight of chlorogenic acid in the raw material as the raw material. 9.09% of the total weight of chlorogenic acid and baicalin, so that the weight of baicalin in the raw material is 90.91% of the total weight of chlorogenic acid and baicalin in the raw material; (2) Scutellaria baicalensis extract and polyethylene glycol 6000 and The stearic acid is mixed, and after heating and melting, the honeysuckle extract is added, and after stirring, a silver-yellow dropping pill is prepared. The polyethylene glycol 6000 is 64.6 times the weight of the chlorogenic acid in the honeysuckle extract. The acid was 4.17 times the weight of chlorogenic acid in the honeysuckle extract.

[0024] See Table 1 for the technological conditions of dripping pills. The better process c...

Embodiment 2

[0031] A Yinhuang Dropping Pill is prepared by the following method: (1) take the honeysuckle extract containing chlorogenic acid and the scutellaria baicalensis extract containing baicalin as raw materials, and make the weight of chlorogenic acid in the raw material as the raw material. 5% of the total weight of chlorogenic acid and baicalin, so that the weight of baicalin in the raw material is 95% of the total weight of chlorogenic acid and baicalin; Glyceryl monostearate is mixed, after heating and melting, the honeysuckle extract is added, and after stirring evenly, a kind of Yinhuang dripping pill is prepared, and the polyethylene glycol 4000 is 50 times the weight of chlorogenic acid in the honeysuckle extract. , glycerol monostearate is 5 times the weight of chlorogenic acid in honeysuckle extract.

Embodiment 3

[0033] A Yinhuang Dropping Pill is prepared by the following method: (1) take the honeysuckle extract containing chlorogenic acid and the scutellaria baicalensis extract containing baicalin as raw materials, and make the weight of chlorogenic acid in the raw material as the raw material. 15% of the total weight of chlorogenic acid and baicalin, so that the weight of baicalin in the raw material is 85% of the total weight of chlorogenic acid and baicalin in the raw material; (2) Scutellaria baicalensis extract, sodium stearate and insect The wax is mixed, and after heating and melting, the honeysuckle extract is added, and after stirring, a silver-yellow dropping pill is prepared. The sodium stearate is 30 times the weight of the chlorogenic acid in the honeysuckle extract, and the insect wax is the honeysuckle extract. 4 times the weight of chlorogenic acid.

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PUM

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Abstract

A Chinese medicine Yinhuang dripping pill is prepared from the extracts of honeysuckle flower and scutellaria root through mixing the extract of scutellaria with polyethylene glycol 6000 and stearic acid, heating for fusing, adding the extract of honeysuckle flower, stirring and preparing dripping pills.

Description

technical field [0001] The invention relates to a traditional Chinese medicine dropping pill and a preparation method thereof. Background technique [0002] In China, drop pills have made some progress in recent years, especially in the field of traditional Chinese medicine pharmaceuticals. Tablets, pills, granules, syrups and other relatively traditional dosage forms are flooding the entire domestic and foreign pharmaceutical markets. Because of their advanced dosage forms and technical content, drop pills high and has not been widely used. [0003] At present, there are compound preparations made of honeysuckle extract and Scutellaria baicalensis extract as the main components, such as granules, oral liquids and capsules. [0004] Through experiments, we found that the active ingredients of the honeysuckle extract are prone to change under long-term high temperature, so the conventional method for preparing drop pills cannot be made into drop pills with stable curative ef...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/539A61K36/35A61K9/20A61P31/00
Inventor 李叔达
Owner TIANJIN ZHONGTIAN PHARMA
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