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Spray agent containing traditional Chinese medicine for treating rhinitis, and its preparation method

A technology of spray and composition, which is applied in the field of traditional Chinese medicine composition and its preparation, can solve the problems that allergic rhinitis has no substantial therapeutic effect, restores the health status gap of nasal mucosa, cannot promote the repair of nasal mucosa tissue, etc., and achieves Convenient transportation, improved extraction rate, and low toxicity

Active Publication Date: 2009-12-23
BUSTER MEDICAL TECH CHANGZHOU CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 1) Most of the existing nasal external preparations cannot promote the repair of the damage caused by the inflammation of the nasal mucosa; although Ditong rhinitis water has a certain effect on the treatment of inflammation of the nasal mucosa, it is far from restoring the health of the nasal mucosa. There is still a big gap in the status
[0007] 2) The existing topical nasal preparations cannot change the pathological condition of nasal mucosa immunohistochemical Bcl-2 to Bax ratio greater than 1, which is unique to allergic rhinitis, and has no substantial therapeutic effect on allergic rhinitis
[0008] 3) The main components of the existing nasal external preparations all contain one or more of the above-mentioned drugs such as ephedra, asarum, cocklebur, angelica dahurica, Shichangpu, saponins, etc., and the above-mentioned drugs have serious side effects or Disadvantages of high toxicity
Saponin has the effect of enlightening people, but it also has side effects. The saponin contained in it is protoplasmic poison and has a strong hemolytic effect. If it is used too much, it will cause poisoning and death due to paralysis of the respiratory center.

Method used

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  • Spray agent containing traditional Chinese medicine for treating rhinitis, and its preparation method
  • Spray agent containing traditional Chinese medicine for treating rhinitis, and its preparation method
  • Spray agent containing traditional Chinese medicine for treating rhinitis, and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0135] Skullcap 170g Magnolia 170g Salvia 100g

[0136] Schisandra 100g Amomum 50g Morus alba 100g

[0137] Prepared to 1000ml. The above raw materials are expanded in proportion, boiled and alcoholized, filtered and purified, and then added with 5 g of Tween-80, 2 g of potassium sorbate and an appropriate amount of glycerin to make a spray.

Embodiment 2

[0138]Example 2, Scutellaria baicalensis 170g, Magnolia magnolia 170g, Salvia miltiorrhiza 100g, Schisandra chinensis 100g, Amomum 50g, Morus alba 100g (proportional expansion during production). Refer to Figure 1: Amomum kernels are crushed into coarse particles and soaked with 10 times the amount of water for 1 hour to extract the volatile oil; the aqueous solution obtained after extracting the volatile oils from Amomum and Magnolia; reflux extraction with 8 times the amount of 80% ethanol for salvia miltiorrhiza and schisandra , each time for 1.5 hours, the alcohol clear ointment obtained; the dregs of Danshen and Schisandra chinensis were decocted with water and decocted together with Scutellaria baicalensis and Morus alba; the water decoction obtained by concentrating the decoction extract was then alcohol Alcoholic ointment is extracted; the above crude drug is added with auxiliary materials, and after being adjusted to 1000ml (proportional expansion in production) with d...

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PUM

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Abstract

A traditional Chinese medicine spray composition for treating rhinitis, raw material composition: Scutellaria baicalensis 150-190g, Magnolia magnolia 150-190g, Salvia miltiorrhiza 80-120g, Schisandra chinensis 80-120g, Amomum 40-60g, Morus alba 80-120g, add auxiliary materials and distilled water Prepared to 1000ml. The raw materials of the optimization scheme all use their extracts: volatile oils from amomum and magnolia; aqueous solution obtained after extracting volatile oils from amomum and magnolia; alcohol-clear ointment obtained by ethanol extraction of salvia miltiorrhiza and schisandra; The water decoction of Scutellaria baicalensis, Scutellaria baicalensis and Morus alba decoction extract are then subjected to alcohol extraction to obtain alcohol clear paste. Made into a spray to cure mainly heat-clearing and damp-drying, tonifying nasal orifices, promoting blood circulation and detumescence, tonifying the lung and restraining qi. For nasal itching, nasal congestion, sneezing and runny nose or nasal congestion, hyposmia, etc.; allergic rhinitis and acute and chronic rhinitis. The present invention also provides a preparation method of the above formula.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine spray composition for treating various rhinitis and a preparation method thereof. Background technique [0002] According to the 1996 survey of 31 member countries of the World Medical Foundation (excluding China), the incidence of allergic rhinitis (ie allergic rhinitis) is about 10%-40%, and there is a trend of increasing year by year. In the UK, patients with allergic rhinitis have increased four-fold in 20 years. In China, it is conservatively estimated that there are more than 40 million patients with allergic rhinitis. The four typical symptoms of allergic rhinitis are nasal congestion, runny nose, nasal itching, and sneezing. These symptoms are related to colds, so many allergic rhinitis (AR) patients are usually mistaken for colds. If patients with misdiagnosed colds or colds are included, the n...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61K36/605A61K36/575A61K36/57A61K36/539A61K36/53A61K9/12A61P11/02
Inventor 张家铭张肇宇储益平
Owner BUSTER MEDICAL TECH CHANGZHOU CO LTD
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