Extract of polysaccharide of lithospermum erthrorhizon and composition containing same and use thereof

A technology of comfrey polysaccharide and extract, applied in the field of medicine

Inactive Publication Date: 2007-08-29
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, it is mainly used for its anti-fertility effect; anti-inflammatory effect, anti-tumor, bactericidal anti-virus; liver protection and immune regulation, and it has also been reported that comfrey polysaccharide has anti-herpes simplex virus type I (HSV-I) effect, but in the treatment of Condyloma acuminatum (CA) caused by human papillomavirus has not been reported yet

Method used

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  • Extract of polysaccharide of lithospermum erthrorhizon and composition containing same and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0129] Example 1 Example of preparation of comfrey polysaccharide

[0130] Take 50g of comfrey, pulverize it, add 15 times the amount of water, reflux and extract at 100°C for 3 times, each time for 1 hour, concentrate the extract to 90mL, cool, and add 95% ethanol under rapid stirring to make the alcohol content reach 80%, then put it at room temperature for more than 24 hours, filter the precipitate to obtain the alcohol precipitation product, then dissolve the precipitate in 100mL of distilled water, heat it at 60°C to fully dissolve, centrifuge at 3000 rpm for 15 minutes, and then discard it by suction filtration To remove the precipitate, add 95% ethanol to the obtained solution to make the alcohol content reach 80%, then place it for more than 24 hours, and filter with suction to obtain the second alcohol precipitation product, and combine the two alcohol precipitation products to obtain comfrey polysaccharide Extract: Add 100 mL of absolute ethanol to the dried comfrey ...

Embodiment 2

[0131] Take 50g of comfrey, pulverize it, add 15 times the amount of water, reflux and extract at 100°C for 3 times, each time for 1 hour, concentrate the extract to 90mL, cool, and add 95% ethanol under rapid stirring to make the alcohol content reach 80%, then put it at room temperature for more than 24 hours, filter the precipitate to obtain the alcohol precipitation product, then dissolve the precipitate in 100mL of distilled water, heat it at 60°C to fully dissolve, centrifuge at 3000 rpm for 15 minutes, and then discard it by suction filtration To remove the precipitate, add 95% ethanol to the obtained solution to make the alcohol content reach 80%, then place it for more than 24 hours, and filter with suction to obtain the second alcohol precipitation product, and combine the two alcohol precipitation products to obtain comfrey polysaccharide Extract.

Embodiment 3

[0132] Example 3 Example of preparation of comfrey polysaccharide

[0133] Take comfrey, reflux for extraction, concentrate the extract, cool, add ethanol, ethanol precipitation, stand still, suction filter to get the precipitate, and obtain the product of alcohol precipitation, then dissolve the precipitate in water, heat it to fully dissolve, centrifuge, Then, the precipitate was discarded by suction filtration, and ethanol was added to the obtained solution, alcohol precipitation, standing, and suction filtration to obtain the second alcohol precipitation product, and the two alcohol precipitation products were combined to obtain the comfrey polysaccharide extract.

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Abstract

The present invention provides a puccoon extract-puccoon polysaccharide and its application in preparation of medicine for effectively curing pointed condyloma. Said medicine has effective action for killing human papilloma virus, so that it can effectively cure the pointed condyloma due to human papilloma virus. Besides, said invention also provides a method for preparing said puccoon polysaccharide by using Chinese medicinal material puccoon.

Description

Technical field [0001] The invention relates to the field of medicine, in particular to a comfrey polysaccharide extract, a composition containing the comfrey polysaccharide extract and uses thereof. Background technique [0002] Condyloma acuminatum (CA for short), also known as condyloma acuminatum or Venereal Warts (Genital Warts), or Anogenital Warts (Anogenital Warts), is a type of wart that mainly occurs on the external genitalia and anus of men and women. Diseases of the skin and mucous membranes. Its incidence rate is increasing year by year, and it has accounted for the second place among sexually transmitted diseases in my country. And the disease has the risk of causing malignant tumors, which seriously endangers the health of the human body, so the disease has attracted more and more attention. [0003] Traditional Chinese medicine believes that condyloma acuminatum belongs to the category of "thousand-day sores", also known as "sore rickets" and "scratch warts...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/30A61K31/715A61P15/02C08B37/00A61K125/00
Inventor 邓远辉
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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