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Chinese traditional medicine soft capsules for relieving cough and method for preparing the same

A technology of soft capsules and traditional Chinese medicines, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., to achieve the effects of convenient application, high bioavailability, and improved bioavailability

Active Publication Date: 2008-01-02
GUIZHOU BAIQIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to: provide a Chinese medicine preparation for relieving cough and its preparation method; the present invention aims at the prior art, and the preparation provided increases drug stability, absorbs quickly, improves high bioavailability, is applicable to a wide range of people, and is convenient for patients to take ; It can also cover up the bad smell of medicines to solve the above problems

Method used

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  • Chinese traditional medicine soft capsules for relieving cough and method for preparing the same
  • Chinese traditional medicine soft capsules for relieving cough and method for preparing the same
  • Chinese traditional medicine soft capsules for relieving cough and method for preparing the same

Examples

Experimental program
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Effect test

Embodiment 1

[0121] Embodiment 1 of the present invention: Chinese phoenix root 300g, ephedra 250g, Hedyotis diffusa 150g, saxifrage 150g, loquat leaf 150g, Cortex Mori 100g, get ephedra 250g and be ground into fine powder, cross 60 mesh sieves (powder yield 90%), 60 After Co radiation sterilization, spare. The remaining five flavors are decocted twice with 8 times the amount of water, 2 hours each time, filtered, concentrated to a relative density of 1.28 (40°C), dried, pulverized, and passed through a 60-mesh sieve (yield is about 15%). Mix ephedra fine powder; add appropriate amount of 2.5% aspartame and dextrin, mix to make granules, and dry to obtain granules.

Embodiment 2

[0122] Embodiment 2 of the present invention: Chinese phoenix root 300g, ephedra 250g, Hedyotis diffusa 150g, saxifrage 150g, loquat leaf 150g, Cortex Mori 100g, get ephedra 250g and be ground into fine powder, cross 60 mesh sieves (powder yield 90%), 60 After Co radiation sterilization, spare. The remaining five flavors are decocted twice with 8 times the amount of water, 2 hours each time, filtered, concentrated to a relative density of 1.28 (40°C), dried, pulverized, and passed through a 60-mesh sieve (yield is about 15%). Mix ephedra fine powder; take 5g of PPVP and mix with lemon yellow, take 3 / 5 PPVP and mix with ointment powder. Use 1.5% K30 absolute ethanol as a binder, make 40 mesh materials, granulate, add the remaining 2 / 5PPVP 2g mixed with tartrazine to the prepared granules, and press into tablets to obtain dispersible tablets .

Embodiment 3

[0123] Embodiment 3 of the present invention: Chinese phoenix root 300g, ephedra 250g, Hedyotis diffusa 150g, saxifrage 150g, loquat leaf 150g, Cortex Mori 100g, get ephedra 250g and be ground into fine powder, cross 60 mesh sieves (powder yield 90%), 60 After Co radiation sterilization, spare. The remaining five flavors are decocted twice with 8 times the amount of water, 2 hours each time, filtered, concentrated to a relative density of 1.28 (40°C), dried, pulverized, and passed through a 60-mesh sieve (yield is about 15%). Mix ephedra fine powder; add appropriate amount of starch, use 60% ethanol and 2% soybean oil to make soft material, and use pellet machine to make soft material. The wet material is squeezed through a 0.8mm sieve hole, and the strip-shaped wet granules are cut and rolled into balls , dried at 50-60°C for molding, passed through a 16-20 mesh sieve, and selected pellets to obtain pellets.

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Abstract

The invention relates to a Chinese pharmaceutical soft capsule for relieving cough and process for preparation, which is prepared from Chinese parasol tree root 300g, Chinese ephedra 250g, oldenlandia 150g, saxifrage 150g, loquat leaves 150g, mulberry bark 100g, soybean oil 1.2 times by weight of the medicament content, the soft capsule also includes a rubber skin consisting of gelatin, glycerin, water and titanium dioxide by a ratio of 100 : 45 : 100 :2, and is prepared through enclosing the medicaments into closed soft rubber shell.

Description

[0001] This application is a divisional application of the patent application for invention submitted by the applicant on October 26, 2005. Technical field: [0002] The invention relates to a traditional Chinese medicine soft capsule for relieving cough and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique: [0003] Various antitussive medicines are many at present, but most of them are western medicines, which are prone to side effects when taken. However, the effect of traditional Chinese medicine for relieving cough is not ideal, and it is inconvenient to take, which brings a lot of troubles to patients. In order to achieve the purpose of treatment, many inventors and pharmaceutical companies have done a lot of research and provided some treatment products; For example, ZL 02134145.1, named "Zhike Capsules and Its Preparation Process", was developed for the treatment of such diseases. However, in the cont...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61K9/48A61K47/42A61P11/14A61K47/10A61K47/14A61K47/32A61K47/34A61K47/36A61K47/38A61K47/44
Inventor 张之君
Owner GUIZHOU BAIQIANG PHARMA
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