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Lung heat-cleaning throat-moistening cough-relieving syrup

A technology for cough syrup, clearing the lungs and relieving the throat, which is applied in drug delivery, plant raw materials, respiratory diseases, etc. It can solve the problems that cannot be directly applied and diseases are rare, and achieve the effect of simple composition, exact curative effect, and small dosage

Inactive Publication Date: 2008-01-09
FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In conclusion, Yangyin Qingfei Decoction has a clear compatibility relationship and significant curative effect, but the original prescription contains a large number of medicinal flavors, which brings many unfavorable factors such as effective substance extraction, quality control, and cost control to large-scale industrial production.
Moreover, the diseases treated by the original prescription are rare, and it cannot be directly applied clinically.

Method used

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  • Lung heat-cleaning throat-moistening cough-relieving syrup
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  • Lung heat-cleaning throat-moistening cough-relieving syrup

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Habitat 27g, Ophiopogon japonicus 36g, Fritillaria 36g, Mint 30g, Honeysuckle (double flower) 24g;

[0013] Preparation method: decoct in regular water.

[0014] [experimental method]

[0015] 1. Using the mouse ear swelling method, 20 male mice were randomly divided into a treatment group and a control group, and were administered by intragastric administration, with a volume of 20ml / kg, once a day for 6 consecutive days. One hour after the last gavage, 20 μl of xylene was applied to the same part of the front and back of the right ear of the mice in each group with a micropipette. After 4 hours, the animals were sacrificed, both ears were cut off, and round ear pieces were respectively punched at the same position with a puncher. Weighed with an electronic balance, and the difference between the weight of the right ear piece and the left ear piece was the degree of swelling. The experimental results were statistically processed using SPSS 13.0 for windows One-Way AN...

Embodiment 2

[0024] Habitat 18g, Ophiopogon japonicus 24g, Chuan Fritillaria 24g, Mint 20g, Honeysuckle (double flower) 16g;

[0025] Preparation method: crush the mint, add 4 times the volume of water to distill for 4 hours to collect the volatile oil, and store the volatile oil in a refrigerator at 4°C. Combine the dregs with raw land, Radix Ophiopogon japonicus, and honeysuckle for regular decoction. Chuanbei 70% ethanol reflux extraction for 4 hours, recovered ethanol, mixed with the aforementioned water decoction and concentrated, added ethanol to 60% and stood still for 24 hours, then concentrated, mixed with volatile oil as the test solution the next day.

[0026] [experimental method]

[0027] 1. Using the mouse ear swelling method, 20 male mice were randomly divided into a treatment group and a control group, and were administered by intragastric administration, with a volume of 20ml / kg, once a day for 6 consecutive days. One hour after the last gavage, 20 μl of xylene was appli...

Embodiment 3

[0036] Habitat 9g, Ophiopogon japonicus 12g, Chuan Fritillaria 12g, Mint 10g, Honeysuckle (double flower) 8g;

[0037] Preparation method: crush the mint, add 4 times the volume of water to distill for 4 hours to collect the volatile oil, and store the volatile oil in a refrigerator at 4°C. Combine the dregs with raw land, Radix Ophiopogon japonicus, and honeysuckle for regular decoction. Chuan Fritillaria was extracted with 70% ethanol under reflux for 4 hours, recovered ethanol, mixed with the aforementioned water decoction and concentrated, added ethanol to 60% and stood still for 24 hours, then concentrated, and mixed with volatile oil as the test solution the next day.

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Abstract

The invention is concerned with the cough syrup for treating Acute and chronic pharyngitis, respiratory tract infections, the materials is with weight sharing: radix rehmanniae is 6 to 12 shares, dwarf lilyturf root is 9 to 15 shares, fritillary bulb is 9 to 15 shares, mint is 7 to 13 shares, and honeysuckle is 5 to 11 shares. The invention is better curative effect, strong pertinency for the above illnesses.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine for treating acute and chronic pharyngitis and cough, itchy throat, sore throat and other diseases caused by respiratory tract infection. Background technique: [0002] The original prescription of Yangyin Qingfei Decoction was first recorded in "Chonglou Yuyao" (written by Zheng Meijian of Qing Dynasty), and it is composed of eight herbs such as Shengdi, Ophiopogon japonicus, Raw licorice, Scrophulariaceae, Fritillaria sichuanensis, Danpi, mint, and fried white peony root. . In the prescription, the raw land sweet and cold enters the kidneys, nourishing yin and clearing away heat, which is the monarch drug; Scrophulariaceae nourishing yin and promoting body fluid, purging fire and detoxification, and Radix Radix nourishing yin and clearing the lungs, which are all ministerial drugs; Yin nourishes blood, Chuan Fritillaria moistens lungs and resolves phlegm, clears heat and dissipates stagnation;...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K9/00A61P11/04
Inventor 王文萍
Owner FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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