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Prescription of mouth ulcer bilayer film and technique of preparing the same

A technology of double-layer film for oral ulcer, which is applied in the field of double-layer film formulation and preparation technology for oral ulcer, can solve the problems of poor anti-relapse effect, large side effects, and insufficient curative effect, and achieve the effect of high curative effect and convenient application

Inactive Publication Date: 2008-03-12
JINAN THE THIRD HOSPITAL
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AI Technical Summary

Problems solved by technology

Because the lesion occurs in the oral cavity and has the characteristics of periodic recurrence, it has a great impact on the patient's physical and mental health, and seriously affects the patient's quality of life.
At present, Western medicine mainly uses immunosuppressants, immune enhancers, sex hormones, vitamins and local cautery in the treatment of recurrent oral ulcers. The side effects are large, the curative effect is not good, and the anti-relapse effect is poor.

Method used

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Embodiment Construction

[0006] The formula of the present invention is: the double-layer film contains 25-40% of coptis, 15-25% of licorice, 12-20% of notoginseng, 12-20% of amomum, 0.15-0.20% of borneol and 8 mint by weight in the double-layer film. ~15%.

[0007] Preparation technique of the present invention is:

[0008] a. Extract volatile oil from Amomum 12-20% and Peppermint 8-15% by weight percentage together by steam distillation, collect the extracted volatile oil, seal and store it for future use.

[0009] b. Mix the residue after extracting volatile oil from amomum and peppermint with 25-40% of rhizoma coptis and 15-25% of licorice by weight, put it in a container, add 5 times the amount of water, soak for 1 hour, and decoct for 1 hour , collect the decoction, add 5 times the amount of water to the residue and decoct for 1 hour, filter with gauze, combine the decoction twice, concentrate the filtrate, add 2-3 times the amount of 85% ethanol, let stand for 24 hours, double-layer The gauze...

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Abstract

The present invention pertains to the art of Chinese medicine, in particular to a recipe of an oral ulcer bilayer formulation and a preparation process. The formulation of the present invention includes the following ingredients in share by weight: 25-40 percents of coptis root, 15-25 percents of liquorice, 12-20 percents of radix notoginseng, 12-20 percents of villous amomum fruit, 0.15-0.20 percents of borneol and 8-15 percents of mint. The preparation process is that the villous amomum fruit and mint are extracted to get a naphtha; the residues, coptis root and liquorice are decocted with water; the radix notoginseng is extracted in an alcohol; all the extracted is merged with borneol, mint oil and PVA added, which is made into a single-layer membrane; then an ethyl cellulose is added to form a bilayer. The present invention has the advantages of nourishing yin and lowering fire, invigorating blood circulation and eliminating stasis, promoting granulation and relieving pain, safety and reliability, convenient use and high curative effect, which can be widely promoted and applied.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a double-layer membrane formula for oral ulcer and a preparation process. Background technique [0002] Recurrent oral ulceration is one of the most common diseases in oral mucosal diseases, ranking first in oral mucosal diseases. Because this lesion occurs in the oral cavity and has the characteristics of periodic recurrence, it has a great impact on the patient's physical and mental health, and seriously affects the patient's quality of life. At present, Western medicine mainly uses immunosuppressants, immune enhancers, sex hormones, vitamins and local cautery for the treatment of recurrent oral ulcers. The side effects are large, the curative effect is also insufficient, and the anti-relapse effect is poor. Contents of the invention [0003] The purpose of the present invention is to develop a formula and preparation process of oral ulcer double-layer...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/70A61K47/32A61K47/38A61P1/02A61K31/02
Inventor 程令梅马春亮郭瑞宝李德民张曙光
Owner JINAN THE THIRD HOSPITAL
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