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Application of brucea javanica oil in preparing medicine for treating chronic gastritis and atrophic gastritis diseases

A technology for atrophic gastritis and chronic gastritis, which is applied in the field of medicine, can solve problems such as difficulty in providing targeted drug treatment, inability to propose systematic treatment methods, and unsatisfactory treatment effects, and achieve ideal treatment effects, low cost, and less recurrence Effect

Inactive Publication Date: 2008-06-04
何宇东
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, no breakthrough has been seen in the treatment of atrophic gastritis by western medicine, but studies have shown that Chinese medicine in my country has unique features in the treatment of gastric ulcer and atrophic gastritis, showing an excellent prospect. However, due to the current etiology and pathology of this disease, In particular, there is no systematic theoretical explanation for the law of evolution. In the process of diagnosis and treatment, a systematic treatment method cannot be proposed, and it is difficult to provide suitable drugs for targeted treatment. The effect is not ideal, and there is a problem that it is easy to recur

Method used

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  • Application of brucea javanica oil in preparing medicine for treating chronic gastritis and atrophic gastritis diseases
  • Application of brucea javanica oil in preparing medicine for treating chronic gastritis and atrophic gastritis diseases
  • Application of brucea javanica oil in preparing medicine for treating chronic gastritis and atrophic gastritis diseases

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0008] The present invention will be further described by pharmacodynamic experiments below.

[0009] 1 test material

[0010] 1.1 Drugs and reagents Brucea javanica oil, provided by the research group; Weiyankang capsules (0.3g / grain), Jilin Kangfu Pharmaceutical Co., Ltd.; hydrochloric acid (analytical pure), Xi’an Chemical Reagent Factory; absolute ethanol (analytical pure ), Xi'an Chemical Reagent Factory.

[0011] 1.2 Animals SD rats, male, weighing 174.7±16.5g, were provided by the Department of Experimental Zoology, Xi'an Jiaotong University.

[0012] 2 Methods and results

[0013] 2.1 Effects on water immersion-restraint stress gastric ulcer in rats

[0014] The rats were randomly divided into 4 groups, namely model control group, small dose of javanica oil (0.5g / kg), large dose of javanica oil (1.0g / kg) and Weiyankang capsule control group (1.2g / kg) In addition to the model control group, the animals in the other groups were administered intragastrically, with a c...

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Abstract

The invention relates to the medicine technical field, in particular to an application of brucea oil in preparing the drugs for treating chronic gastritis and atrophic gastritis. Brucea oil is widely applied as an anticancer drug and the safty for oral administration can be proved, so the invention is safe and reliable.The brucea of the quassia has wide source and so the cost is low; through the experiment, the brucea oil performs very well, the treatment effect is ideal and patients can be cured by taking according to the course of treatment without recurrence easily.

Description

Technical field: [0001] The invention relates to the technical field of medicine, in particular to the application of javanica javanica oil in the preparation of medicines for chronic gastritis and atrophic gastritis. Background technique: [0002] Chronic gastritis and atrophic gastritis are common diseases of the digestive system, and the incidence rate in my country is extremely high. Gastroscopic surveys have confirmed that the incidence rate of chronic gastritis in the Chinese population is as high as 60%, and atrophic gastritis accounts for about 1 / 5 of them. Disease tends to increase with age. Investigate its cause of disease is intricate, motherland's medical science thinks that it is mostly caused by reasons such as exogenous evil invading the stomach, eating disorder or internal injury of emotion, constitution deficiency. This disease not only affects the daily life of the patient, but more importantly, it is one of the precancerous states of the stomach. If it is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P1/04
Inventor 何宇东
Owner 何宇东
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