Unlock instant, AI-driven research and patent intelligence for your innovation.

Apparatus and method for separating and combination

A technology for separating chambers and additional components, applied in the field of devices and methods for separating components, capable of solving problems such as impossibility of obtaining WBCs, contamination of WBCs, etc.

Active Publication Date: 2008-06-18
PRECISIONBIOSENSOR INC
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Accordingly, it is not possible to obtain sufficient quantities of WBCs, and WBCs can become contaminated during these manipulations depending on the skill level of the operator

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Apparatus and method for separating and combination
  • Apparatus and method for separating and combination
  • Apparatus and method for separating and combination

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0051] The present invention will now be described more fully with reference to the accompanying drawings, in which exemplary embodiments of the invention are shown.

[0052] FIG. 2 is a plan view of an apparatus 100 for separating components according to an exemplary embodiment of the present invention.

[0053]Referring to FIG. 2 , the apparatus 100 includes a disc-shaped base 110 with a radius of about 6 cm and a spindle motor 105 that rotates the base 110 . The substrate 110 includes a plurality of component separation units 111 arranged at equiangular intervals about the axis of the substrate 110 . Each fractionation unit 111 includes a main chamber 115 that is generated from the axis of the substrate 110 in parallel to the centrifugal force F generated by the rotation of the substrate 110 (see FIG. 3B ), a fractionation chamber 125, and a waste chamber 130. The direction extends radially. The fractionation unit 111 also includes a first channel 126 connecting the fract...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
melting pointaaaaaaaaaa
Login to View More

Abstract

An apparatus for separating components and a method of separating components using the apparatus are provided. The apparatus includes: a main chamber which contains a sample that is separated into a plurality of layers by a centrifugal force; a component separating chamber which is connected to the main chamber, and receives a specific layer including specific components among the plurality of layers; a first channel which connects the component separating chamber to the main chamber; and a first channel valve which is disposed in the first channel to control a liquid flowing through the first channel.

Description

technical field [0001] The devices and methods of the invention relate to the separation of specific components from a sample. Background technique [0002] Recently, isolation of specific components, such as white blood cells (WBCs) from whole blood (WB), has been widely used as a method for diagnosing various diseases. Specific components, such as WBCs, can be extracted from a sample such as blood by chemically extracting components that are not specific components in succession until only the specific components remain, or by separating the sample into layers according to the components , thereby separating a specific layer including a large amount of a specific component by centrifugation. [0003] 1A and 1B are cross-sectional views sequentially showing a related art method of separating WBCs from WB by centrifugation. [0004] Referring to Figure 1A, to extract WBCs from WC, inject 100 μl of density gradient medium (DGM) 20 reagent into tube 10, and dilute the dilute...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/28G01N1/34
CPCB01D59/20
Inventor 朴钟勉金秉澈
Owner PRECISIONBIOSENSOR INC