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Chinese thorowax Shugansan oral preparation and preparing method thereof

A technology of Chaihu Shugan powder and oral preparations, which is applied in the field of medicine, can solve the problems of inaccurate dosage, inability to commercialize, inconvenient to carry and take, etc., and achieve good curative effect and wide application effect

Inactive Publication Date: 2008-07-30
BEIJING JINFANGHUA MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The ancient Bupleurum Shugan San did not only have a decoction. It needs to be decocted and taken after purchasing the decoction pieces. It is very inconvenient to carry and take it. After research, we made a modern oral preparation of traditional Chinese medicine through quantitative control of the index components. The product dosage is accurate and the quality is stable. , easy to take, suitable for large-scale commercial production, overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize, and is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1: Preparation method of Bupleurum Shugan Powder Extract 1 (extract and volatile oil)

[0047] Prescription: Bupleurum 6g, Chenpi 6g, Ligusticum chuanxiong 5g, Cyperus cyperi 5g, Fructus aurantium 5g, Peony 5g, Radix Glycyrrhizae 3g

[0048] Preparation method: cleanly select various medicinal materials for the prescription, weigh each medicinal material according to the prescription amount, add 6 to 15 times the amount of water to soak for 2-10 hours, heat and slightly boil for extraction 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to get the supernatant, concentrated under reduced pressure to obtain a medicinal extract of about 8.5 g of water extract and about 0.2 g of volatile oil.

Embodiment 2

[0049] Example 2: Preparation method of Bupleurum Shugan Powder Extract 2 (dry powder and volatile oil)

[0050] Prescription: Bupleurum 6g, Chenpi 6g, Ligusticum chuanxiong 4.5g, Rhizoma Cyperi 4.5g, Fructus aurantium 4.5g, Peony 4.5g, Radix Glycyrrhizae 1.5g

[0051] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8 to 10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, the supernatant was filtered, concentrated under reduced pressure, and spray-dried to obtain a dry powder of about 6.0 g of water extract and about 0.15 g of volatile oil.

Embodiment 3

[0052] Example 3: Preparation method of Bupleurum Shugan powder oral solid preparation

[0053] (1) Preparation of Bupleurum Shugan Powder Granules

[0054] prescription:

[0055] Bupleurum Shugan Powder Extract 1 10-90%

[0056] Starch 5.0-70%

[0057] Dextrin 2.0-20%

[0058] Xylitol 5.0-20%

[0059] Methyl sorbate 0.001-2.0%

[0060] Preferred Prescription:

[0061] Bupleurum Shugan Powder Extract 1 8.5g

[0062] Starch 3.0g

[0063] Dextrin 3.0g

[0064] Xylitol 2.0g

[0065] Methyl sorbate 0.002g

[0066] Preparation method: Prepare the Chai Bupleurum Shugan powder extract according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, pack and make Into two bags, each bag 8.25g.

[0067] (2) prepare Bupleurum Shugan Powder tablet:

[0068] (1) Ordinary tablet pre...

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PUM

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Abstract

The invention relates to an oral preparation of Chaihushugan powder, which is prepared with Chinese thorowax root and other six Chinese medicines mainly for treating stagnation of hepatic qi, and the preparation method thereof. The oral preparation is prepared according to conventional processes and utilizing the mixed extracts (extractum or drymeal and naphtha) of bupleurum, tangerine peel, szechuan lovage rhizome, nutgrass galingale rhizome, bitter orange, peony and radix glycyrrhizae preparata as raw materials, together with vector or excipient which are utilized as matrix and acceptable in pharmacy. The preparation has the effects of relieving liver qi stagnation, promoting qi and relieving pain, and mainly treats liver qi depression. The long-term clinical application of the prescription shows that the oral preparation has a good effect on chronic hepatitis, chronic gastritis and cholecystitis, etc.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral preparation for mainly treating stagnation of liver qi and a preparation method thereof, in particular to an oral preparation using the extract of the traditional Chinese medicine prescription of Bupleurum Shugan Powder as the active ingredient. Background technique [0002] "Chaihu Shugan Powder" was created by Ye Wenling in the Ming Dynasty's "Medical Tongzhi". It has always been used as a common prescription for soothing the liver and relieving depression. , has the effects of soothing the liver and relieving depression, promoting qi and relieving pain, and is mainly used to treat stagnation of liver qi. The long-term clinical application of the prescription shows that it has a good curative effect on chronic hepatitis, chronic gastritis, cholecystitis, etc., and has a wide range of applications, and no obvious side effects have been found. [0003] The s...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61K9/48A61K9/20A61K9/16A61K9/10A61K9/28A61K9/46A61K47/38A61K47/34A61K47/32A61P1/16A61P1/04A61K47/10A61K47/36A61K47/44
Inventor 张文芳
Owner BEIJING JINFANGHUA MEDICAL SCI TECH
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