Preparation method for externally used ophicalcitum compound emergency life saving hemostatic

The technology of stamen and hemostatic agent is applied in the field of preparation of emergency life-saving hemostatic agent of external stamen compound, and achieves the effects of good hemostatic effect, improved hemostasis performance and promotion of thrombosis.

Active Publication Date: 2009-01-14
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there are no domestic and foreign patent reports on the application of stamens and their compounds in blood coagulation materials, wound t

Method used

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  • Preparation method for externally used ophicalcitum compound emergency life saving hemostatic
  • Preparation method for externally used ophicalcitum compound emergency life saving hemostatic
  • Preparation method for externally used ophicalcitum compound emergency life saving hemostatic

Examples

Experimental program
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Effect test

Embodiment 1

[0036] Example 1

[0037] A certain amount of stamen is put into a Chinese medicine pulverizer, and the pulverization time is about 5 minutes; the particle size of the pulverized particles is 1 micron to 1 mm. Dry the crushed stamen in an oven at 100°C for 1 hour. Its hemostatic effect is good. See attached Figure 4 , 5 , 6.

Embodiment 2

[0039] A certain amount of stamen was roasted at 300°C, 500°C, 700°C, and 900°C for 6 hours to obtain heat-treated stamen. The above stamens were dried in an oven at 100°C for 24 hours. The stamen has a good hemostatic effect in the range of 100~500℃, and its hemostatic effect is shown in the attached file. image 3 .

Embodiment 3

[0041] Combine the crushed stamen with 1.0mol / L CaCl 2 Mix at a solid-liquid ratio of 1g / 20m, react at room temperature for 24 hours, wash with deionized water, and dry in an oven at 100°C for 24 hours to obtain modified calcium-rich stamen. Its hemostatic effect is significantly better than that of stamen raw ore. See attached for hemostatic effect Figure 4 .

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Abstract

The present invention provides a preparation method of an external-use ophicalcitum compound emergency hemostat. The present invention grinds the natural ophicalcitum into a certain particle diameter, carries out the calcium chloride modification treatment through different temperature treatments, and obtains the ophicalcitum compound material with high hematopoietic function by mixing with other auxiliary compound materials. The present invention can be used for hemostasis on different medical occasions, can be combined with other medical materials and medical apparatuses, can be made into adhesive bandage, transfusion bandage, self-adhesive dressing, tablet and capsule core material, operation packet, first-aid packet, etc., and can also be made as the oral medicine and be used with other external-use medicines so as to get better curing effect. The present invention has the advantages of simple and feasible operation, abundant materials, low price and easy access, convenient application, good hematopoietic effect and less discharged heat.

Description

Technical field [0001] The invention relates to an emergency life-saving hemostatic agent for treating fatal hemorrhage of large blood vessels that cannot be controlled by conventional hemostasis measures and a preparation process thereof, in particular to a preparation method of an emergency life-saving hemostatic agent of external use stamen complex. Background technique [0002] Emergency life-saving hemostatic agents are an emerging research field in the world. Emergency life-saving hemostatic agents are mainly developed for emergencies in which the blood flow does not stop in trauma. In a short period of time (3 minutes), emergency situations like aortic bleeding can be controlled, and valuable time can be obtained for further medical treatment. [0003] According to statistics from the Ministry of Health in 2007, about 200 million people of various injuries occur every year, and the death toll from injuries such as wars, traffic accidents, and major natural disasters is abo...

Claims

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Application Information

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IPC IPC(8): A61K33/10A61P7/04A61L15/44A61K33/06
Inventor 范杰李云龙
Owner ZHEJIANG UNIV
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