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Compound Cordyceps sinensis oil soft capsule and preparation technique

A technology of Cordyceps oil and soft capsules, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of complicated process, unsafe, flammable ethanol, etc., to improve the absorption rate and enhance the strengthening effect , the effect of easy industrialization

Inactive Publication Date: 2009-04-15
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the process, ethanol solution is used to granulate and dry, the process is complicated, and ethanol is flammable and unsafe

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Mix 4kg of Cordyceps powder and 3kg of crushed wood particles (particle size: 5.5mm), put them into an extraction kettle, extract for 3 hours at 28MPa, 40°C, and after secondary separation, 57.2g of Cordyceps oil is released from the separation kettle, with an oil yield of 1.43 %.

[0028] Implementation column 2

[0029] Mix 4kg of Cordyceps powder and 2.5kg of glass beads (particle size: 5mm), put them in an extraction kettle, extract at 28MPa, 40°C for 3 hours, and release 51.6g of Cordyceps oil from the separation kettle after secondary separation, with an oil yield of 1.29%. .

Embodiment 3

[0031] Mix 4kg of Cordyceps powder and 2kg of stainless steel (particle size 4mm), put them in an extraction kettle, extract for 3 hours at 28MPa, 40°C, and after secondary separation, 60.8g of Cordyceps oil is released from the separation kettle, with an oil yield of 1.52%.

Embodiment 4

[0033] Put the gelatin in a plastic tank, add first-grade glycerin in distilled water, heat to 85°C and stir, after the gelatin is completely dissolved, add preservatives and antioxidants, stir evenly, degas and keep warm at 65°C to obtain soft Capsule capsule material glue; according to the weight ratio of the ingredients, it is 100mg of Cordyceps oil, 20mg of Cordyceps powder, 90mg of black currant oil, 90mg of garlic oil, 100mg of pine nut oil. Further mixing to obtain the content of the soft capsule; the above-mentioned capsule material, glue and liquid content are pressed into a soft capsule by a soft capsule machine, and after shaping, screening, cleaning and drying, the Cordyceps oil compound soft capsule is obtained.

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Abstract

The invention discloses a compound soft capsule of cordyceps oil and a process for preparing the same. An improved supercritical carbon dioxide process is adopted to extract the cordyceps oil which is used as a main active ingredient to be prepared into the compound soft capsule. The process is simple and is easy to realize industrialization, the extracted cordyceps oil has high transparency, the maximum oil yield reaches 1.5 percent, and no organic solvent is used in extraction to ensure the natural activity of the cordyceps oil; and the formulation combination of the compound soft capsule is novel and unique, and is based on scientific original creation to effectively improve the effect of functional components, thus the strengthening effect of the functional components is improved, the absorption rate of effective factors by a human body is improved, and the medicinal function is greatly improved.

Description

technical field [0001] The invention improves the process of extracting cordyceps oil by supercritical carbon dioxide, and also provides a compound soft capsule preparation of cordyceps oil by using the cordyceps oil as a main raw material, belonging to the technical field of extraction and application of effective components of traditional Chinese medicines. Background technique [0002] Cordyceps sinensis (Cordyceps sinensis) is a valuable Chinese herbal medicine. Traditional Chinese medicine believes that Cordyceps is sweet and flat in nature and taste, nourishing deficiency and benefiting essence. Modern drug research shows that Cordyceps contains 18 kinds of amino acids, including 8 kinds of amino acids necessary for the human body, and vitamin B 12 Wait, it can nourish the body. The cordycepin and cordycepic acid possessed by Cordyceps have the functions of improving and promoting collective immune function, sedation, anti-convulsion, anti-tumor effect, anti-pathogen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/068A61P3/00A61P13/12A61P25/20A61P29/00A61P31/00A61P37/04
Inventor 滕利荣逯家辉孟庆繁张晗思蒋振彦张益波王贞佐
Owner JILIN UNIV
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