Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Tibetan medicine pill for influenza as well as quality criteria and inspection method of preparation thereof

A quality control method, influenza technology, applied in pharmaceutical formulations, antiviral agents, measuring devices, etc., can solve the problems of poor specificity and reproducibility

Active Publication Date: 2009-08-12
GANSU CHEEZHENG TIBETAN MEDICINE CO LTD
View PDF0 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the original standard, the identification of Tibetan calamus and horned fennel was carried out using a unified extraction method and developer. The specificity and reproducibility of the standard are poor, and the standard detection method needs to be improved urgently.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Tibetan medicine pill for influenza as well as quality criteria and inspection method of preparation thereof
  • Tibetan medicine pill for influenza as well as quality criteria and inspection method of preparation thereof
  • Tibetan medicine pill for influenza as well as quality criteria and inspection method of preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] A. Thin-layer identification of horn fennel

[0085] Take 3 g of this pharmaceutical composition, grind it finely, add 1 ml of ammonia water, add 20 ml of chloroform, shake well, extract ultrasonically for 30 minutes, filter, evaporate the filtrate to dryness, add 2 ml of chloroform to the residue to dissolve it, and use it as the test solution; 1 g of fennel reference medicinal material, according to the preparation method of the test solution to prepare the reference solution; according to the prescription ratio and preparation process, prepare a negative sample without fennel, and according to the preparation method of the above test solution to prepare the negative sample solution According to thin-layer chromatography ("Chinese Pharmacopoeia" 2005 edition an appendix VIB) test, draw each 0.005ml of the above-mentioned three solutions, respectively point on the same silica gel G thin-layer plate, with chloroform-methanol-cyclohexane 7: 3:1 is the developing agent, t...

Embodiment 2

[0089] A. Take 2 parts by weight of the pharmaceutical composition, grind finely, add 3 parts by volume of ammonia water, add 10 parts by volume of chloroform, shake well, extract by cold immersion for 45 minutes, filter, evaporate the filtrate, add 1 part by volume of chloroform to the residue to make Dissolve, as the test solution; take another 1.2 parts by weight of carnation reference medicinal material, make reference solution according to the preparation method of the test solution; according to the prescription ratio and preparation process, prepare a negative sample that does not contain carnation, and follow The preparation method of above-mentioned need testing solution makes negative sample solution; According to thin-layer chromatography ("Chinese Pharmacopoeia" 2005 edition one appendix VI B) test, draw each 0.004 volume part of above-mentioned need testing solution, respectively point on the same silica gel On the G thin-layer plate, chloroform-methanol-cyclohexan...

Embodiment 3

[0092] A. Thin-layer identification of horn fennel

[0093] Take 12 g of this pharmaceutical composition, grind it finely, add 0.5 ml of ammonia water, add 35 ml of chloroform, shake well, extract by cold immersion for 10 minutes, filter, evaporate the filtrate to dryness, add 8 ml of chloroform to the residue to dissolve it, and use it as the test solution; Take 0.5 g of carnation reference medicinal material, and prepare a reference solution according to the preparation method of the test solution; according to the prescription ratio and preparation process, prepare a negative sample that does not contain carnation, and prepare according to the preparation method of the above test solution. Negative sample solution; according to thin-layer chromatography (Appendix VIB of the 2005 edition of the Chinese Pharmacopoeia) test, draw 0.015ml of the above-mentioned test solution and negative sample solution, and 0.002ml of the control medicinal material solution, respectively, point...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a flu pill of Tibetan medicine and a quality control method of a preparation thereof; wherein the preparation is various preparation formulations which are made by adding conventional excipients according to the conventional technique and the formulation of the flu pill in fascicule of Tibetan medicine of Standards of Medicine of the Ministry of Public Health. The quality control method comprises one or more of identification methods. The invention carries out thin layer chromatogram identification study on hypecoum erectum and bhizoma acori calami in the formulation, establishes the quality control method with reliability, accuracy and strong specificity, can effectively control the quality of the flu pill and enable the flu pill to achieve stable, controllable, high-effective and safe quality.

Description

technical field [0001] The invention relates to a quality standard and a testing method for a pharmaceutical composition preparation, in particular to a quality standard and a testing method for Tibetan medicine flu pills and their preparations. Background technique [0002] Tibetan medicine flu pills are composed of twenty-one herbs including myrobalan, myrobalan, horn fennel, Tibetan calamus, rhubarb, chuanmuxiang, chrysanthemum, artificial musk, artificial bezoar, etc. It retains the active ingredients of the medicine and reflects the characteristics of Tibetan medicine. Function: Clearing away heat and detoxifying, it has its unique curative effect on the runny nose, headache, cough, body aches, inflammation and fever caused by influenza. Influenza Pills are included in the "Medical Standards of the Ministry of Health" Tibetan Medicine Volume, the standard number: WS3-BC-0327-95. In the original standard, the identification of Tibetan calamus and horn fennel adopts a u...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P31/16A61P11/00G01N30/90A61K35/02A61K35/55A61K35/413
Inventor 包旭宏拉果才让
Owner GANSU CHEEZHENG TIBETAN MEDICINE CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com