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Antibiotic artificial hip joint

A technology of hip joint and antibiotics, applied in the field of artificial hip joint, can solve the problems of no obvious effect of antibiotics, economic loss of patients, toxic reactions, etc., and achieve the effect of completely killing bacteria, improving curative effect and treating infection

Inactive Publication Date: 2009-09-02
ARMY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After infection, the artificial hip joint will form a biofilm, and the systemic intravenous administration or topical application of antibiotics has no obvious effect, and it will also produce toxic reactions
Revision surgery is needed to replace the artificial hip joint that has been infected with bacteria, which undoubtedly brings huge pain and economic loss to the patient
So far, there is no simple and feasible solution both at home and abroad.

Method used

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  • Antibiotic artificial hip joint

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Such as figure 1 As shown, an antibiotic artificial hip joint is composed of an acetabular prosthesis, a femoral head, and an artificial hip joint handle 3. The artificial hip joint handle 3 is provided with the same pipe 4, and one end of the pipe 4 is connected from the artificial hip The upper part of the joint handle 3 passes through to communicate with the outside world, and the outer surface of the artificial hip joint is provided with a micropore 2, and the micropore 2 communicates with a tube 4, which is filled with a silica sol slow-release agent solution adsorbed with antibiotics. Antibiotics are various antibiotics such as penicillin or vancomycin or gentamycin or teicoplanin or cephalosporin. A disc 5 is sheathed at the end of the pipe 4 passing through. The antibiotics are cephalosporins, β-lactams, aminoglycosides, vancomycin, teicoplanin and other antibiotics. The preparation of the described silica sol sustained-release agent with antibiotics is to pre...

Embodiment 2

[0014] Such as figure 1 As shown, an antibiotic artificial hip joint is composed of an acetabular prosthesis, a femoral head, and an artificial hip joint handle 3. The artificial hip joint handle 3 is provided with the same pipe 4, and one end of the pipe 4 is connected from the artificial hip The upper part of the joint handle 3 passes through to communicate with the outside world, and the outer surface of the artificial hip joint is provided with micropores 2, and the micropores (2) communicate with the tube 4, which is filled with the silica sol slow-release agent solution adsorbed with antibiotics . Antibiotics are penicillin or vancomycin or gentamicin or teicoplanin or cephalosporin. A disc 5 is sheathed at the end of the pipe 4 passing through. The antibiotics are cephalosporins, β-lactams, aminoglycosides, vancomycin, teicoplanin and other antibiotics. The preparation of the silica sol sustained-release agent with antibiotics is to prepare 50g / L antibiotic solution ...

Embodiment 3

[0016] Such as figure 1 As shown, an antibiotic artificial hip joint is composed of an acetabular prosthesis, a femoral head, and an artificial hip joint handle 3. The artificial hip joint handle 3 is provided with the same pipe 4, and one end of the pipe 4 is connected from the artificial hip The upper part of the joint handle 3 passes through to communicate with the outside world, and the outer surface of the artificial hip joint is provided with a micropore 2, and the micropore 2 communicates with a tube 4, which is filled with a silica sol slow-release agent solution adsorbed with antibiotics. Antibiotics are penicillin or vancomycin or gentamicin or teicoplanin or cephalosporin. A disc 5 is sheathed at the end of the pipe 4 passing through. The antibiotics are cephalosporins, β-lactams, aminoglycosides, vancomycin, teicoplanin and other antibiotics. The preparation of the silica sol slow-release agent with antibiotics is to prepare 25g / L antibiotic solution with distill...

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PUM

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Abstract

The invention discloses an antibiotic artificial hip joint which comprises acetabulum prosthesis, femoral heads and an artificial hip joint handle (3), wherein a same tube (4) is arranged in the artificial hip joint handle (3), one end of the tube (4) perforates out of the upper part of the artificial hip joint handle (3) and is communicated with exterior, a micropore (2) is arranged on the outer surface of an artificial hip joint and communicated with the tube (4), and the tube (4) is filled with silica sol sustained release agent solution absorbed with antibiotic. The antibiotic artificial hip joint directly inhibits the forming and the maturity of biomembrane, changes the original using way that the antibiotic is used in general veins and partially and externally used, improves the anti-infectious healing efficacy and obviously reduces the toxic reaction and can regularly supplement and replace effective antibiotic and achieve the aims of thoroughly killing bacteria and radically curing infection on the promise of not replacing the prosthesis after operation, thereby not only playing prevention and cure roles to patients, but also curing the infection.

Description

technical field [0001] The invention belongs to an artificial hip joint for orthopedics, in particular to an artificial hip joint which can be injected with silica sol antibiotics. Background technique [0002] After femoral head necrosis or femoral neck fracture, hip replacement surgery is required, and an artificial hip joint made of titanium alloy or other materials is inserted into the human body for replacement. After the artificial hip joint is implanted into the human body, many patients will experience some complications, such as infection, dislocation, loosening, and fracture. After infection, the artificial hip joint will form a biofilm, and the systemic intravenous administration of antibiotics or topical application of antibiotics has no obvious effect, and it will also produce toxic reactions. Just need to carry out revision operation again, replace the artificial hip joint that has been infected with bacteria, this has brought huge misery and economic loss to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/32A61K38/14A61K31/7028A61K31/546A61K31/397A61P31/04
CPCA61F2/36A61F2002/30001
Inventor 王爱民唐良华杜全印孙红振
Owner ARMY MEDICAL UNIV
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