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Application of dendrobium officinale aqueous extract in preparing medicine for preventing and treating hypertension and apoplexy

A technology of Dendrobium officinale and water extract, applied in the application field of water extract of Dendrobium officinale and medicine, can solve the problems such as the function of lowering blood pressure and preventing cerebral apoplexy, which can prevent stroke, lower blood pressure, and alleviate persistent blood pressure. Effect

Active Publication Date: 2009-12-30
ZHEJIANG TIANHUANG MEDICINAL PLANT PHARMA
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AI Technical Summary

Problems solved by technology

However, other traditional pharmacopoeias and modern literature have no record of the function of lowering blood pressure and preventing cerebral apoplexy

Method used

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Experimental program
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Effect test

Embodiment Construction

[0040] 1. Materials and methods of animal experiments:

[0041] 1. Dendrobium candidum water extract: provided by Zhejiang Tianhuang Pharmaceutical Co., Ltd., batch numbers: 070612, 070620, 070717.

[0042] 2. Hypertensive animal model rats: stroke-prone spontaneously hypertensive rats (SHR-sp) were used. The pathological characteristics of SHR-sp hypertension are similar to those of severe hypertension in the human body. The disease develops rapidly and is prone to stroke. SHR-sp is obtained from the offspring of SHR who died of stroke through inbreeding selection. Without additional incentives (common diet feeding), stroke can occur within 9 to 13 months, and the incidence rate can be as high as 90%. The pathological changes in the occurrence and development of hypertension and stroke are very similar to those of humans, which can better reflect the effects of drugs on the human body. The above-mentioned model rats were provided by the Shanghai Animal Center of the Chinese...

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Abstract

The invention relates to an application of dendrobium officinale, aiming at disclosing an application of a dendrobium officinale aqueous extract in preparing a medicine for preventing or treating hypertension and apoplexy. The invention also provides dipping paste, particles, capsules, tablets and oral liquid which are suitable for the novel application and are prepared by utilizing the dendrobium officinale aqueous extract and relevant preparation methods. The applied dendrobium officinale aqueous extract has a moderate and permanent function of lowering blood pressure of a white rat with hereditary apoplexy type spontaneous hypertension and can prolong the survival time thereof, enhance the survival rate and prevent apoplexy, and the relevant medicine effect function has a certain relativity with the use quantity of the dendrobium officinale aqueous extract. The dendrobium officinale aqueous extract is utilized as a medicine with a specific application, can lower the blood pressure of a patient with hypertension moderately and permanently, delays the evolution of hypertension class cerebrovascular injuries and is of great significance for human beings to prevent the hypertension and the apoplexy and lower the mutilation rate and the fatal rate of the hypertension.

Description

technical field [0001] The invention relates to the use of dendrobium candidum, in particular to the application of the dendrobium candidum water extract in the preparation of medicines for preventing or treating hypertension and stroke. Background technique [0002] Hypertension is a common high incidence, and the prevalence rate is increasing year by year. At present, there are about 200 million hypertensive patients in my country. With the acceleration of the pace of life, changes in dietary structure, and lack of exercise, the age of onset is advancing year by year, and the incidence is further increasing. As the disease progresses, high blood pressure often damages important vital organs such as the brain, heart, and kidneys, leading to functional changes and organic damage, and even disability and death. Stroke is one of the severe hypertensive organ damages. Among the current Chinese and Western medicines for the prevention and treatment of hypertension, while contro...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61K9/48A61K9/16A61K9/00A61K9/20A61K9/06A61P9/12A61P7/02A61K135/00
Inventor 陈立钻楼正家吴人照杨兵勋张旭峰沈春香夏克中杨方亮余善凯陈午兵王增陈宇郑纯威李端阳
Owner ZHEJIANG TIANHUANG MEDICINAL PLANT PHARMA
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