Kendir pressure-reducing sticking agent and preparation method thereof
A technology of apocynum and transdermal patches, which is applied in the field of pharmaceutical preparations and can solve problems such as large drug loading, skin allergies, and molding process that limit the development of traditional Chinese medicine patches.
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Embodiment 1
[0015] Preparation of patch
[0016] prescription
[0017] Apocynum 370g, Prunella vulgaris 80g, Uncaria 80g, Alisma 70g, mother-of-pearl 50g, Achyranthes bidentata 50g, hawthorn 50g, chrysanthemum 50g
[0018] Polyvinyl alcohol 20g, gelatin 30g, kaolin 3g, glycerin 150g, azone 40g
[0019] Preparation Process:
[0020] (1) Preparation of the active ingredient of the crude drug: mother of pearl is pulverized, passed through a 120 mesh sieve, and set aside; the medicinal materials Apocynum apocynum, Prunella vulgaris, Alisma, hawthorn and chrysanthemum are respectively pulverized into coarse powder, mixed evenly, and mixed with 70% The ethanol reflux extracts 3 times, each 2 hours, filters, and merges extract, and filtrate reclaims ethanol under reduced pressure, concentrates to the thick ointment that relative density is 1.20, and thick ointment adds 95% ethanol, fully stirs, and makes medicinal solution contain The alcohol content is 80%, stand still, filter, take the supe...
Embodiment 2
[0024] Preparation of patch
[0025] prescription
[0026] Apocynum 300g, Prunella vulgaris 100g, Uncaria 100g, Alisma 100g, mother-of-pearl 30g, Achyranthes bidentata 30g, hawthorn 30g, chrysanthemum 30g
[0027] Polyvinyl alcohol 10g, gelatin 20g, kaolin 1g, glycerin 300g, azone 50g
[0028] Preparation Process:
[0029] (1) Preparation of the active ingredient of the crude drug: mother of pearl is pulverized, passed through a 120-mesh sieve, and set aside; the medicinal materials Apocynum apocynum, Prunella vulgaris, Alisma, hawthorn and chrysanthemum are respectively pulverized into coarse powder, mixed evenly, and mixed with 60% The ethanol reflux extracts 2 times, each 3 hours, filters, and merges extracting solution, and filtrate reclaims ethanol under reduced pressure, concentrates to the thick ointment that relative density is 1.10, and thick ointment adds 95% ethanol, fully stirs, and makes medicinal solution contain The alcohol content is 60%, stand still, filter...
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