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Novel process for Chinese medicinal composition for reducing blood fat and method for preparing novel formulations

A composition and blood lipid-lowering technology, applied in the directions of drug combination, pharmaceutical formula, drug delivery, etc., can solve the problems of high price, easy rebound, short course of treatment, etc., and achieve the effects of novel dosage form, scientific process, and controllable process quality.

Inactive Publication Date: 2010-01-13
北京天骄奥特奇中蒙药工程技术研究有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Imported lipid-lowering drugs Tetiaozhi and Zhikangping have good curative effect and short course of treatment, but they are also expensive. Toxic reactions, especially to the liver, cannot be ignored, and they are easy to rebound in a short period of time after stopping the drug

Method used

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  • Novel process for Chinese medicinal composition for reducing blood fat and method for preparing novel formulations

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Take 90g of Radix Polygoni Multiflori, 90g of Semen Cassiae, 60g of Rhubarb, 80g of Puhuang, 40g of Longan, 90g of Pueraria, 45g of Astragalus, 80g of Turmeric, 95g of Alisma, 85g of Curcuma, 45g of Trichosanthes Fensis, 95g of Salvia miltiorrhiza, 90g of Chinese yam, and grind them into pieces. Sieve and pack directly into capsules. 0.45g / capsule, take 4 capsules each time.

Embodiment 2

[0033] Take 100g of Radix Polygoni Multiflori, 90g of Semen Cassiae, 50g of Curcuma, 45g of Alisma, 50g of Curcuma, 50g of Salvia miltiorrhiza, 40g of Trichosanthum Fensis, and 50g of Chinese yam, crushed, and sieved through an 80-mesh sieve for later use. Take 70g of rhubarb, 85g of Puhuang (packet), 45g of longan longan, 90g of kudzu root, 100g of astragalus, 50g of turmeric, 45g of Alisma, 50g of turmeric, 50g of salvia miltiorrhiza, 40g of trichosanthin, and 50g of Chinese yam. Extract 2 times with 60% ethanol, 1.5 hours for the first time, 1 hour for the second time, combine the extracts, concentrate until the density of the extract is 1.3, add to the fine powder of the previous part of the medicinal materials, dry at 80°C, and pass through 80°C after crushing. Mesh sieve, made into capsules. 0.40g / capsule, take 4 capsules each time.

Embodiment 3

[0035] Take 95g of Radix Polygoni Multiflori, 90g of Semen Cassiae, 23g of Turmeric, 23g of Alisma, 22g of Curcuma, 25g of Salvia miltiorrhiza, 12.5g of Trichosanthes chinensis, and 30g of Chinese yam in 25% of the prescribed amount, grind them, and pass through an 80-mesh sieve for later use. Take 60g of rhubarb, 100g of Puhuang (packet), 50g of longan longan, 80g of kudzu powder, 90g of astragalus, 69g of turmeric, 69g of Alisma, 66g of turmeric, 37.5g of trichosanthes, 75g of salvia miltiorrhiza, and yam 90g, extract with 80% ethanol for 1.5 hours, 70% ethanol for 1.5 hours, 60% ethanol for 1 hour, combine the extracts, concentrate until the extract density is 1.2, add to the fine powder of the previous part of medicinal materials, and dry at 80°C , crushed and passed through a 80-mesh sieve, granulated, and compressed into tablets. 0.45g per tablet, 4 capsules each time.

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Abstract

The invention discloses a novel process for a Chinese medicinal composition for reducing blood fat and a method for preparing novel formulations. Different formulations are prepared by different extraction methods. Medicinal materials are partially or fully extracted by ethanol in different proportions according to a prescription to prepare hard capsules, soft capsules, tablets and sustained-release preparations respectively. By adopting the modern technology, the novel process and the method improve the technical content of the medicament, ensure that the active ingredients of each medicinal material can be fully extracted, and provide the safe, effective and controlled medicament for reducing the blood fat. The method can provide more choices for wide patient groups through the research of the different formulations, and at the same time, the dosage is reduced; and the Chinese medicinal composition is taken, stored and transported conveniently, and satisfies the patient.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition derived from plant materials, more specifically to a blood lipid-lowering traditional Chinese medicine composition and a preparation method thereof with a new process and a new dosage form. Background technique [0002] In recent years, the number of patients with cardiovascular and cerebrovascular diseases in middle-aged and elderly people has increased, and blood rheological examination shows that the blood viscosity index exceeds the standard. Because hyperlipidemia can easily cause myocardial infarction, cerebral thrombosis and other diseases that seriously endanger people's lives. Therefore how to make the problem of hyperlipidemia patients approaching the normal value has aroused the general concern of the scientific research workers in the medical field. [0003] Unsaturated fatty acids are the most commonly used lipid-lowering drugs clinically in our country, such drugs includ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/20A61K9/22A61K9/48A61K47/32A61P3/06G01N30/90G01N30/36
Inventor 王兰英
Owner 北京天骄奥特奇中蒙药工程技术研究有限公司
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