Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for preparing female silkworm moth powder with high estradiol content

A technology with high estradiol and estradiol, which is applied in the field of preparation of silkworm female moth powder, achieves positive social and economic benefits, meets diversified needs, and has remarkable therapeutic effects

Inactive Publication Date: 2010-02-17
ZHEJIANG UNIV
View PDF0 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hormone replacement therapy is a method that uses exogenous estrogen or estrogen combined with progesterone to delay or alleviate women's menopause syndrome. Although its curative effect has been confirmed clinically, long-term use will produce a series of obvious adverse effects including the induction of cancer. response, the risks of which have attracted widespread attention

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] In spring, use suitable ripe mulberry leaves to raise silkworms of the 54A variety in a clean environment at 25-28°C (27-28°C for the 1st-2nd age, 26°C for the 3rd-4th age, and 25°C for the 5th age) until the cocoons are formed in the upper cocoon. After pupation, the cocoons were cut open, and silkworm chrysalis were taken out for male and female identification. Female silkworm chrysalis were subcutaneously injected with 20-hydroxyecdysone (dose 4 μg / head) in the abdomen on the second day of pupation. Spray the female silkworm chrysalis evenly with 75% ethanol solution every hour, and seal it for 3 hours. Continue to protect from darkness at 24-25°C. After 21 hours, light-sensitize the female silkworm chrysalis to emerge. After 5 hours of emergence, vibrate to allow the female silkworm moth to empty the moth urine, and move it into a refrigerator. Gradually lower the temperature to -30°C within 2 hours. Freeze at ℃. The frozen female silkworm moth was vacuum-dried at ...

Embodiment 2

[0020] In spring, use suitable ripe mulberry leaves to raise silkworms of the 54A variety in a clean environment at 25-28°C (27-28°C for the 1st-2nd age, 26°C for the 3rd-4th age, and 25°C for the 5th age) until the cocoons are formed in the upper cocoon. After pupation, the cocoons were cut open, and silkworm chrysalis were taken out for male and female identification. The female silkworm chrysalis was subcutaneously injected with 20-hydroxyecdysterone (dose 5 μg / head) in the abdomen on the second day of pupation, and 24 hours before eclosion. Spray the female silkworm chrysalis evenly with 75% ethanol solution every hour, and seal it for 3 hours. Continue to shading protection at 24-25°C. After 21 hours, light-sensitize the female silkworm chrysalis to emerge. After 5 hours of emergence, vibrate to allow the female silkworm moth to empty the moth urine, and move it into a refrigerator. Gradually lower the temperature to -30°C within 4 hours. freezing. The frozen female silk...

Embodiment 3

[0022] In spring, use suitable ripe mulberry leaves to raise silkworms of the 54A variety in a clean environment at 25-28°C (27-28°C for the 1st-2nd age, 26°C for the 3rd-4th age, and 25°C for the 5th age) until the cocoons are formed in the upper cocoon. After pupation, the cocoons were cut open, and silkworm chrysalis were taken out for male and female identification. The female silkworm chrysalis was subcutaneously injected with 20-hydroxyecdysterone (dose 5 μg / head) in the abdomen on the second day of pupation, and 24 hours before eclosion. Spray the female silkworm chrysalis evenly with 75% ethanol solution every hour, and seal it for 3 hours. Continue to protect from darkness at 24-25°C. After 21 hours, light-sensitize the female silkworm chrysalis to emerge. After 5 hours of emergence, vibrate to allow the female silkworm moth to empty the moth urine, and move it into a refrigerator. Gradually lower the temperature to -30°C within 2 hours. Freeze at ℃. The frozen femal...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for preparing female silkworm moth powder with high estradiol content, which comprises the following steps: raising a silkworm by mulberry leaves till the silkworm climbs a cluster and cocoons; after the silkworm is pupated, opening a cocoon; taking a silkworm pupa out to carry out sex authentication; protecting a female silkworm pupa in the normal environment; inthe second day of pupation, hypodermically injecting 20-hydroxy ecdysterone to the abdomen of the female silkworm pupa, wherein each female silkworm pupa is injected with 4-5 micrograms of 20-hydroxyecdysterone; in 24 hours before eclosion, uniformly spraying a silkworm pupa body by 75 percent of alcohol liquid and sealing for 3 hours; in 5 hours after eclosion, freezing, drying, ultramicro-pulverizing and preparing the female silkworm moth powder with high estradiol content. The prepared female silkworm moth powder has high estradiol content, obvious therapeutic effect on a climacteric syndrome and positive social and economic benefits, can be used for developing a treating medicine or health food for preventing and treating the woman climacteric syndrome so as to meet the diversified requirement at home and abroad for the treating medicine or the health food of the woman climacteric syndrome and can improve the traditional sericulture.

Description

technical field [0001] The invention relates to a preparation method of silkworm female moth powder with high estradiol content. Background technique [0002] Menopausal syndrome is a group of symptoms caused by the decrease of estrogen secretion in women, which causes endocrine disorders and autonomic disorders. Symptoms such as instability, insomnia, forgetfulness, irritability and suspiciousness, fatigue and cramps, osteoporosis, dull skin, increased cholesterol, and increased psychological stress not only seriously endanger physical and mental health, but also seriously affect work, husband and wife relationships, and family happiness. With the acceleration of the pace of human life and the deepening of aging, in recent years, the age of menopause has become younger and the number of menopausal syndromes has increased rapidly, which has become a global medical topic and social public health problem. [0003] At present, clinical treatment of menopausal syndrome mainly i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K35/64A61P15/12A61P5/30A01K67/04
Inventor 时连根李有贵顾美儿贺伟强金卫明费建明李玉峰
Owner ZHEJIANG UNIV
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com