Orthopedic internal fixation plate and preparation method thereof

A fixed plate and orthopedic technology, applied in the field of medical materials, can solve the problems of affecting the recovery effect, prone to displacement, slipping, and increasing the pain of patients, achieving good biocompatibility and wear resistance, preventing adhesion, and relieving pain Effect

Active Publication Date: 2010-06-02
CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The surface of the traditional splint used clinically is a flat structure, which is different from the arc structure of the spine. It is prone to displacement and slippage after long-term use, which will affect the recovery effect and increase the pain of the patient.

Method used

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  • Orthopedic internal fixation plate and preparation method thereof
  • Orthopedic internal fixation plate and preparation method thereof
  • Orthopedic internal fixation plate and preparation method thereof

Examples

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Effect test

preparation example Construction

[0026] The preparation method of the orthopedic internal fixation plate provided by the invention comprises:

[0027] a) Make the mold of the orthopedic internal fixation plate, so that the cross-section of the side of the produced orthopedic internal fixation plate in contact with the spine is an arc that matches the spine. For details, please refer to figure 1 .

[0028] b) Put the biodegradable polymer material into the mould, and perform compression molding. The biodegradable polymer material is preferably PLLA or a mixture of PLLA and HA, and the weight ratio of PLLA to HA in the mixture of PLLA and HA is preferably 8:1˜11:1.

[0029] Preferably, before putting the above biodegradable polymer materials into the mould, it also includes heating PLLA or the mixture of PLLA and HA to 180°C to 200°C and stirring and mixing evenly, because the PLLA used in the preparation process Organic solvents, so there will always be residual solvents in the finished PLLA, which can be re...

Embodiment 1

[0032] First prepare the mold. Then the PLLA was heated to 180°C in a torque rheometer and stirred evenly. Take out the PLLA and put it into the mold, mold it at 190°C and 9.5MPa for 2.5min, then cool down to 120°C, keep it warm for 1.5min, then cool down to room temperature and take out the molded fixing plate. After testing, the impact strength of the obtained orthopedic internal fixation plate is 7.8±0.94KJ / m 2 . The orthopedic internal fixation plate was transplanted into animals for experiments, and the impact strength after 7 months of transplantation was 6.99±1.42KJ / m 2 .

Embodiment 2

[0034] First prepare the mold. Then, PLLA and HA with a weight ratio of 9:1 were heated to 190° C. in a torque rheometer and stirred and mixed. Take out the mixture of PLLA and HA and put it into a mold, mold it at 195°C and 10MPa for 2min, then cool down to 118°C, keep it warm for 1min, then cool down to room temperature and take out the molded fixing plate.

[0035] After testing, the impact strength of the obtained orthopedic internal fixation plate is 7.46±0.4KJ / m 2 . The orthopedic internal fixation plate was transplanted into animals for experiments, and the impact strength after 7 months of transplantation was 14.75±0.9KJ / m 2 .

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Abstract

The invention provides an orthopedic internal fixation plate. The cross section on one side contacted with the backbone is an arc matched with the backbone, and the orthopedic internal fixation plate is made of PLLA or composite material of PLLA and HA. A preparation method for the orthopedic internal fixation plate comprises the following steps: a) manufacturing a die, and enabling the cross section of the orthopedic internal fixation plate on the one side contacted with the backbone to be the arc matched with the backbone; and b) putting a biodegradable polymer material into the die, and performing compression molding. The orthopedic internal fixation plate has a shape of a certain radian matched with the backbone aiming at the structure of the backbone of a human body, and can be effectively attached to the shape of the vertebral column, reconstruct and recover the stability of the vertebral column, prevent adhesion and slipping displacement, and relieve the pain of patients; and the orthopedic internal fixation plate made of the biodegradable polymer material has good biocompatibility and abrasion resistance, can be retained in the human body for long term, finally can be fully biodegraded, and does not need to be taken out through a secondary operation.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to an orthopedic internal fixation plate and a preparation method thereof. Background technique [0002] Patients with spinal fractures or who have undergone surgery on the spine need to be splinted and then bandaged after the surgical site has been reduced. The surface of the traditional splint used clinically is a flat structure, which is somewhat different from the arc-shaped structure of the spine. Long-term use is prone to displacement and slippage, which in turn affects the recovery effect and increases the pain of the patient. Contents of the invention [0003] The problem to be solved by the present invention is to provide an orthopedic internal fixation plate, which has a shape that matches the spine, can effectively fit the shape of the spine, rebuild and restore the stability of the spine, prevent slippage and displacement, and reduce the pain of the patient. The inven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/80A61L31/06A61L31/12A61L31/14
Inventor 章培标王宗良陈学思崔毅高战团崔立国王宇
Owner CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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