The invention provides a clamp suitable for multiple sizes for cutting processing equipment, and relates to the technical field of cutting processing equipment. The clamp comprises two fixed seats, the middle parts of the fixed seats are filled with electrorheological fluid, rubber surfaces are fixedly connected to the inner sides of the fixed seats, and protection surfaces fixedly connected withthe inner sides of the rubber surfaces are fixedly connected to the inner sides of the fixed seats. According to the clamp suitable for the multiple sizes for the cutting processing equipment, throughthe cooperation usage of the electrorheological fluid and a piston block, when materials are clamped, the materials are placed between the two fixed seats, then the two fixed seats move to the middlepart, so that the materials are clamped by the fixed seats, and the materials can be fully wrapped according to the shape of the materials due to the fact that the electrorheological fluid is at a liquid state at the moment. Meanwhile, the extruded electrorheological fluid is fully extruded into a buffer slot, the piston block is moved, after the materials are taken down, the piston block can revert under the action of a first spring, so that the clamp effectively fits the materials, the clamping effect is improved, multi-size application is achieved, reusing can be achieved, and the practicability is improved.