The invention discloses a concentrated solution freezing
crystallization machine for salifying preparation of
erythromycin oxime, and relates to the technical field of salifying preparation of
erythromycin oxime, the concentrated solution freezing
crystallization machine comprises a rack, a supporting plate is fixedly connected to the position, close to the edge, of the bottom of the rack, and a guide sliding groove is formed in the lower position of the surface of the supporting plate; and the top of the rack is fixedly connected with a hoist. According to the concentrated solution freezing crystallizer for salifying preparation of
erythromycin oxime, a cavity is formed in the position between the temperature adjusting
assembly and the temperature slowing
assembly, heating water is introduced into the cavity, erythromycin oxime salt is evaporated and concentrated through water bath heating, then hot water is discharged to enable the temperature of a concentrated solution to reach a metastable area, and the interior of the temperature slowing
assembly is slowly cooled; the erythromycin oxime crystals are separated out, the electric rotary table drives the magnetic sliding block to rotate, the temperature slowing assembly scrapes off the adhered crystals, and the problems that the
heat transfer performance is deteriorated and the yield of the erythromycin oxime is low due to the fact that
crystal scales are very easy to crystallize between a cooled solution and a
heat transfer surface are solved.