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Ultrasonic coupling agent and application thereof

A technology of ultrasonic coupling agent and bactericide, which is applied in the field of clinical medical testing, can solve the problems that cannot meet the detection of cavities, mucous membranes and incomplete skin, low irritation, high safety, etc., and achieve low cost of raw materials and low irritation , high safety effect

Inactive Publication Date: 2010-06-02
GUANGDONG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, due to the high risk of cross-infection during ultrasound detection and ultrasound-assisted treatment of cavities, mucous membranes, incomplete skin, and acupuncture, higher requirements are placed on the coupling agent in direct contact. In addition to the functions of ultrasonic impedance, non-corrosion of the probe, and disinfection and sterilization of the probe, the coupling agent used must have extremely low irritation, extremely weak toxicity, and high safety requirements for the cavity, mucous membrane, and incomplete skin, etc.
[0008] Chinese patents CN1087016A, CN1108956A and CN200710078112.9, etc., all provide ultrasonic coupling agents with disinfection and sterilization, but these ultrasonic coupling agents cannot meet the needs of detecting cavity, mucous membrane and incomplete skin

Method used

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  • Ultrasonic coupling agent and application thereof

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Comparison scheme
Effect test

Embodiment 1

[0037] The ultrasonic coupling agent of the present embodiment, its raw material is made up of each component of following parts by weight:

[0038] Silver nitrate 0.2g

[0039] Hydroxyethylcellulose 25.0g

[0040] Amino Acid Zinc 5.0g

[0041] Sodium polyphosphate 5.0g

[0042] Allantoin 1.0g

[0043] Deionized water 963.8g

[0044] The total amount is 1000g

[0045] The preparation method of the present embodiment ultrasonic coupling agent, its steps are as follows:

[0046] Dissolve amino acid zinc, allantoin and sodium polyphosphate in deionized water, add hydroxyethyl cellulose, stir until the liquid is transparent, add silver nitrate solution, stir and mix well, adjust the pH of the whole system to 5-7 with NaOH , vacuum degassed, canned.

Embodiment 2

[0048] The ultrasonic coupling agent of the present embodiment, its raw material is made up of each component of following parts by weight:

[0049] Silver nitrate 0.2g

[0050] Carbomer 5.0g

[0051] Zinc acetate 5.0g

[0052] Sodium polyphosphate 5.0g

[0053] Allantoin 1.0g

[0054] Deionized water 983.8g

[0055] The total amount is 1000g

[0056] The preparation method of the present embodiment ultrasonic coupling agent, its steps are as follows:

[0057] Dissolve zinc acetate, allantoin, and sodium polyphosphate in deionized water in a sugar porcelain stirring pot, add carbomer, stir, and when the liquid is transparent, add silver nitrate solution, stir and mix well, add an appropriate amount of NaOH solution to adjust the pH and viscosity, control the pH of the whole system to 5-7, vacuum degassing, and canning.

Embodiment 3

[0059] The ultrasonic coupling agent of the present embodiment, its raw material is made up of each component of following parts by weight:

[0060]Nano Silver Colloid 0.5g

[0061] Carbomer 5.0g

[0062] Zinc acetate 5.0g

[0063] Sodium polyphosphate 5.0g

[0064] Allantoin 1.0g

[0065] Deionized water 983.5g

[0066] The total amount is 1000g

[0067] The preparation method of the present embodiment ultrasonic coupling agent, its steps are as follows:

[0068] Add part of deionized water to zinc acetate, allantoin and sodium polyphosphate in the sugar porcelain stirring pot, then add nano-silver colloid dispersed in advance, stir to dissolve, then add carbomer, make up the remaining amount of deionized water, Homogeneously disperse, add appropriate amount of NaOH solution to adjust pH and viscosity, control the pH of the whole system to 5-7, vacuum degassing, and pack in cans.

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Abstract

The invention discloses an ultrasonic coupling agent and application of the ultrasonic coupling agent in ultrasonic inspection or auxiliary treatment of clinical cavity canals, mucous membranes, non-intact skin and the like in hospital. The ultrasonic coupling agent consists of the following raw materials: safe and nontoxic silver ions or nanometer silver serving as a disinfectant, and bio-compatibility macromolecular materials serving as a viscosity regulator, an anti-discoloration agent, an anti-precipitant agent, and an anti-stimulant agent. The ultrasonic coupling agent meets the requirements on ultrasonic impedance and no corrosion, has the characteristics of disinfection, sterilization, safety, nontoxicity, no stimulation and the like, can effectively avoid cross infection in ultrasonic clinics, can be suitable for detecting the cavity canals, the mucous membranes and the non-intact skin, and has high medical clinical value. The ultrasonic coupling agent has a simple preparation method, and low cost of raw materials.

Description

technical field [0001] The invention relates to the technical field of clinical medical detection, in particular to ultrasonic detection technology for clinical cavity, mucous membrane and incomplete skin in hospitals, and in particular to an ultrasonic coupling agent and ultrasonic detection for clinical cavity, mucosa and incomplete skin in hospitals or in adjuvant therapy. Background technique [0002] Medical ultrasonic coupling agent is used in clinical ultrasonic diagnosis, and acts as a coupling between the transmitting probe and the measured object, so that sound waves can enter the body smoothly to obtain reliable images. The basic requirement is that it can effectively transmit sound waves, its acoustic impedance is close to that of human tissue, the sound wave attenuation is small, clear images can be obtained, and there is no damage to the ultrasonic probe, it is easy to spread, and it is non-toxic and non-irritating to the human body. Easy to scrub. [0003] S...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22A61K33/38A61K31/4166A61K36/185
Inventor 杜志云张焜莫容清汤志凯
Owner GUANGDONG UNIV OF TECH
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