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Antiatherosclerotic Chinese traditional medicine for treating cardiovascular and cerebrovascular diseases and method for preparing phospholipid complex formulation thereof

A technology for cardiovascular and cerebrovascular diseases and atherosclerosis, which is applied in the field of traditional Chinese medicine preparations and its preparation, can solve problems that cannot meet the actual needs of patients and restrict the development of traditional Chinese medicine preparations for cardiovascular and cerebrovascular diseases, and improve the technical level and the quality of clinical medication, the enhancement of antihypertensive and anti-inflammatory effects, and the effect of large drug loading

Inactive Publication Date: 2010-06-09
刘秀芬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many kinds of traditional Chinese medicine preparations for treating cardiovascular and cerebrovascular diseases. However, due to various reasons, such as curative effect, absorption, drug loading, etc., the development of existing traditional Chinese medicine preparations for treating cardiovascular and cerebrovascular diseases is restricted, and they cannot be well developed. Meet the actual needs of patients and solve the pain of patients.

Method used

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  • Antiatherosclerotic Chinese traditional medicine for treating cardiovascular and cerebrovascular diseases and method for preparing phospholipid complex formulation thereof
  • Antiatherosclerotic Chinese traditional medicine for treating cardiovascular and cerebrovascular diseases and method for preparing phospholipid complex formulation thereof
  • Antiatherosclerotic Chinese traditional medicine for treating cardiovascular and cerebrovascular diseases and method for preparing phospholipid complex formulation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Example 1: A traditional Chinese medicine for anti-atherosclerosis and treating cardiovascular and cerebrovascular diseases, which consists of the following components in weight percentage: chuanxiong 59%, kudzu root 37%, notoginseng total saponins 0.5%, red yeast rice 3.5%.

[0058] The preparation method of the phospholipid complex preparation of the above-mentioned Chinese medicine:

[0059] (1) Preparation of Radix Puerariae Dry Extract

[0060] The Pueraria lobata medicinal material of the above percentage is crushed into a coarse powder, refluxed and extracted with 70% ethanol three times, and the time of each refluxed extraction is 1 hour, and then the three obtained extracts are combined, and the ethanol is recovered under reduced pressure and concentrated to form The primary concentrated solution is then diluted with water to form the upper column liquid containing 0.2g kudzu root medicinal material per milliliter, and the upper column liquid is passed through ...

Embodiment 2

[0066] Example 2: A traditional Chinese medicine for anti-atherosclerosis and treating cardiovascular and cerebrovascular diseases, which is composed of the following components in weight percentage: Rhizoma Chuanxiong 79%, Radix Puerariae 17%, Total Panax notoginseng Saponins 1%, Monascus 3%.

[0067] The preparation method of the phospholipid complex preparation of the above-mentioned Chinese medicine:

[0068] (1) Preparation of Radix Puerariae Dry Extract

[0069] Pueraria puerariae medicinal materials of the above percentage are crushed into coarse powder, refluxed and extracted with 70% ethanol three times, and the time of each refluxed extraction is 2 hours, and then the extracts obtained from the three times are combined, and the ethanol is recovered under reduced pressure and concentrated to form The primary concentrated solution is then diluted with water to form the upper column liquid containing 0.2g kudzu root medicinal material per milliliter, and the upper colum...

Embodiment 3

[0075] Example 3: A traditional Chinese medicine for anti-atherosclerosis and treating cardiovascular and cerebrovascular diseases, which consists of the following components in weight percentage: 60% of Rhizoma Chuanxiong, 35% of Pueraria Radix, 1% of Panax notoginseng saponins, and 4% of Monascus.

[0076] The preparation method of the phospholipid complex preparation of the above-mentioned Chinese medicine:

[0077] (1) Preparation of Radix Puerariae Dry Extract

[0078] Pueraria puerariae medicinal materials of the above percentage are crushed into coarse powder, refluxed and extracted with 70% ethanol three times, and the time of each refluxed extraction is 3 hours, then the extracts obtained from the three times are combined, and the ethanol is recovered under reduced pressure and concentrated to form The primary concentrated solution is then diluted with water to form the upper column liquid containing 0.2g kudzu root medicinal material per milliliter, the upper column ...

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Abstract

The invention relates to an antiatherosclerotic Chinese traditional medicine for treating cardiovascular and cerebrovascular diseases, comprising the following components of szechuan lovage rhizome, the root of kudzu vine, Panax notoginsenosides and red yeast rice. The method for preparing phospholipid complex formulation of the antiatherosclerotic Chinese traditional medicincomprises (1) preparation of dry extract of the root of kudzu vine, (2) preparation of szechuan lovage rhizome oil and dry extract of Ligusticum wallichii and (3) preparation of formulation. By enriching effective parts of medicinal materials, the purity of effective components of the antiatherosclerotic Chinese traditional medicine is enhanced greatly, thereby meeting the request of formulation. The invention is formed by trial of medicinal effectiveness separation and innovation of the medicine and realizes organic combination of traditional formulation process and modern pharmaceutical technology, thereby not only enhancing medicine-loading rate but also enhancing bioavailability of medicine used by a human body.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine preparation capable of treating cardiovascular and cerebrovascular diseases and resisting atherosclerosis, specifically a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and its phospholipid complex Preparation method of drug preparation. Background technique [0002] In today's society, due to the accelerated pace of life and the popularity of unhealthy lifestyles, the incidence of cardiovascular and cerebrovascular diseases is increasing year by year, and has a younger trend. It has become a disease with the highest prevalence, disability and mortality, and a serious threat. affecting people's health and life. Therefore, controlling the spread of cardiovascular and cerebrovascular diseases has become a top priority. The main cause of cardiovascular and cerebrovasc...

Claims

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Application Information

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IPC IPC(8): A61K36/48A61K47/24A61K9/48A61P9/10
Inventor 刘秀芬尹昆尹斌尹峰尹世英
Owner 刘秀芬
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