The invention discloses a preparation method and a quality detection method of a vinegar rhizoma
corydalis standard decoction, and relates to the technical field of
quality research of traditional Chinese medicinal materials. The preparation method comprises the following steps: weighing a proper amount of vinegar-processed rhizoma
corydalis decoction pieces, putting into a marmite, decocting twice, adding 9 times of water for soaking for 30 minutes for the first time, boiling with strong fire, and decocting with
slow fire for 30 minutes; 7 times of water is added for the second time, the mixture is boiled with strong fire and then decocted with
slow fire for 20 min, the liquid
medicine is filtered with 200 meshes, the filtrate is cooled to the
room temperature in a cold water bath, the two filtrates are combined, vacuum concentration is conducted at the temperature of 50 DEG C, vacuum concentration is conducted at the absolute vacuum degree of 30-40 mbar until the weight ratio of the medicinal materials to the
fluid extract is about 1: 1, concentrated liquid is collected, and
freeze drying is conducted to obtain a sample. According to the method, key quality indexes such as the main content, the characteristic chromatogram and the extract of the vinegar rhizoma
corydalis after the decoction is prepared are measured, the transfer rate is investigated, the component transfer condition from decoction pieces to the decoction is measured through
objective quality standards, and the quality degree and effectiveness of the decoction are ensured.