Mass continuous safe production diazomethane reactor and working method thereof

Abstract

The invention relates to a mass continuous safe production diazomethane reactor, which consists of a cavity body, a reaction center I, a reaction center II, a raw material A dripping port, a raw material B dripping port, a N2 air suction bubbling tube, a diazomethane discharging tube, a cooling jacket, a cooling medium inlet, a cooling medium outlet and a waste liquid discharging tube, wherein the cavity body consists of an upper seal end a reactor wall and a lower seal end. Working method comprises the following steps that: (1) diazald and NaOH enter the reaction center I inside the cavity body of the reactor respectively through the raw material A dripping port and the raw material B dripping port to be contacted and reacted with each other to generate diazomethane; (2) reaction liquid inside the reaction center I slowly flows into the reaction center II from an overflow port above the reaction center I, the raw materials which are not completely reacted are continuously reacted with each other to generate the diazomethane gas during the process. The reactor has the advantages that: under the condition that the explosion danger is reduced, the device has simple structure, mass and continuous production of the diazomethane can be realized, and the diazomethane is free from being stored and can be directly used.

Description

(1) Technical field: [0001] The invention relates to a diazomethane reactor, in particular to a large-scale continuous and safe production of diazomethane reactor and a working method thereof. (two) background technology: [0002] The chemical formula of diazomethane is CH 2 N 2 , is very active in nature and can undergo various types of reactions. It is an important reagent in organic synthesis, mainly used for organic synthesis intermediates (methyl substituents), and also for the preparation of methylene carbene. The boiling point of liquid diazomethane is -23°C. Diazomethane can be dissolved in ether, and its ether solution is relatively stable. The ether solution of diazomethane is often used in synthesis. [0003] Since diazomethane is highly toxic and explosive, special care should be taken when preparing and using it. The obstacles to the industrial production of diazomethane are: [0004] 1. Diazomethane is unstable and explosive, and cannot be stored for a long...

AI Technical Summary

Problems solved by technology

[0004] 1. Diazomethane is unstable and explosive, and cannot be stored for a long time. It should be put into the next reaction immediately after preparation. It will cause explosion when it encounters light, acid, rough surface, or high concentration.

[0005] 2. Diazomethane is toxic and can cause cancer. Inhalation of diazomethane and skin or eye contact with diazomethane are toxic (TLV 0.2ppm). Symptoms include heart discomfort, headache, physical weakness, and physical exhaustion. person passed out

However, because the reaction produces high-purity diazomethane liquid and needs to be stored at a strict temperature, it increases safety hazards in the industrial production process

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