Vena cava shunt and portacaval transfer anticoagulation catheter and preparation method thereof
A vena cava and catheter technology, applied in the field of vena cava shunt and portacaval bypass anticoagulation catheter and its preparation, can solve the problems of poor blood compatibility, congestion in the middle and lower parts of the body and visceral damage, reduce the tension of the tube wall, etc., and achieve Effects of reducing wall tension, maintaining stability, and widening the surgical field of view
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[0021] A preparation method of an anticoagulation catheter for vena cava shunt and portacaval bypass, the steps are as follows:
[0022] Step 1: Clean the surface of the medical polyvinyl chloride pipe with ethanol ultrasonically for 5 hours to 8 hours, then wash it with distilled water for 4 hours to 6 hours, and dry it naturally to obtain the medical polyvinyl chloride pipe with the cleaned surface;
[0023] Step 2: Take an aqueous solution with a mass ratio of 40% of polyethyleneimine and add glutaraldehyde and absolute ethanol with a mass ratio of 25% to prepare a 2.5wt% polyethyleneimine ethanol solution;
[0024] Step 3: Completely immerse the medical polyvinyl chloride pipe with the surface cleaned in 2.5wt% polyethyleneimine ethanol solution, soak it at 40°C-45°C for 4 hours to 6 hours, and dry it under vacuum at room temperature to obtain the surface bonded Polyethyleneimine medical polyvinyl chloride pipes;
[0025] Step 4: preparing a heparin aqueous solution with ...
Embodiment 1
[0030] Embodiment 1: A preparation method of an anticoagulation catheter for vena cava shunt and portacaval bypass, the steps are as follows:
[0031] Step 1: The surface of the medical polyvinyl chloride pipe is ultrasonically cleaned with ethanol for 5 hours, and then cleaned with distilled water for 4 hours, and the medical polyvinyl chloride pipe with the cleaned surface is obtained after natural air drying;
[0032] Step 2: Take an aqueous solution with a mass ratio of 40% of polyethyleneimine and add glutaraldehyde and absolute ethanol with a mass ratio of 25% to prepare a 2.5wt% polyethyleneimine ethanol solution;
[0033] Step 3: The medical polyvinyl chloride pipe with the surface cleaned is completely immersed in 2.5wt% polyethyleneimine ethanol solution, soaked at 40°C for 4 hours, and then dried under vacuum at room temperature to obtain the medical polyvinyl chloride pipe with the surface bound to polyethyleneimine. PVC piping;
[0034] Step 4: preparing a hepari...
Embodiment 2
[0038] Embodiment 2: A preparation method of anticoagulation catheter for vena cava shunt and portacaval bypass, the steps are as follows:
[0039] Step 1: Clean the surface of the medical polyvinyl chloride pipe with ethanol for 6 hours, then wash it with distilled water for 5 hours, and dry it naturally to obtain the medical polyvinyl chloride pipe with the cleaned surface;
[0040] Step 2: Take an aqueous solution with a mass ratio of 40% of polyethyleneimine and add glutaraldehyde and absolute ethanol with a mass ratio of 25% to prepare a 2.5wt% polyethyleneimine ethanol solution;
[0041] Step 3: The medical polyvinyl chloride pipe with the surface cleaned is completely immersed in a 2.5wt% polyethyleneimine ethanol solution, soaked at 41 ° C for 5 hours, and then dried under vacuum at room temperature to obtain a medical polyvinyl chloride pipe whose surface has been bound to polyethyleneimine. PVC piping;
[0042] Step 4: preparing a heparin aqueous solution with a mas...
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