Swing-driven circular cell culture device

A cell culture and circulation technology, applied in tissue cell/virus culture devices, special-purpose bioreactors/fermenters, biochemical instruments, etc., can solve the problems of complex operation, high shear force, and high price. Achieve simple and effective circulation, small circulation shear force, and good manufacturing process
CN101974424AInactive Publication Date: 2011-02-16ZHENGZHOU VIRIGE BIOTECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHENGZHOU VIRIGE BIOTECH
Publication Date
2011-02-16
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a swing-driven circular cell culture device. The culture device comprises a hard culture container the lower part of which is provided with a solution chamber; the bottom surface of the solution chamber is a smooth concave surface; a slope surface is arranged on the side wall surface of the solution chamber; the slope surface and the concave surface are in smooth transition; a circular pipe is arranged on the side wall of the solution chamber along the slope surface in a matched manner; the circular pipe is provided with an upper opening and a lower opening; and a one-way discharge valve structure is arranged at the lower opening. When the circular cell culture device is driven to swing left and right, the upper culture solution constantly enters from the upper openings of the two circular pipes and rushes out from the lower openings, while the original lower culture solution is turned upwards in the process to realize up-down circulation of the culture solution; the circulation is simple and effective, and the mixing and ventilation effect is good; and moreover, the circulation frequency can be minimized and the shearing force of the circulation is little.
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Description

technical field

[0001] The present invention relates to a cell culture device in which a culture liquid circulates when a rocking drive is applied to it. Background technique

[0002] The cultivation of organisms (including the cultivation of animal cells, plant cells, insect cells and microorganisms) and the use of the above-mentioned cultured organisms for biotechnology products (such as proteins, polypeptides, nucleic acids, antibodies, virus vectors and virus vaccines) ) production, it is necessary to provide appropriate temperature, necessary gases (such as oxygen and carbon dioxide gas) and proper mixing, so there are various products on the market that are suitable for it, such as incubators, carbon dioxide incubators, mixing shakers , fermenters, culture bottles and various cell bioreactors, etc. When performing cell culture, especially animal cell culture and the use of animal cells for the production of the above-mentioned biotechnology products, precise temperatu...

Claims

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