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Preparation method and application of macaranga tanarius extract

An extract, the technology of Macaranga tanarius, applied in the field of preparation of Macaranga tanarius extract, can solve the problems of paclitaxel resource shortage and high price, achieve low price, reduce production cost, and inhibit tumor growth

Active Publication Date: 2012-01-04
广东瀚森生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] One of the purposes of the present invention is to provide a method for preparing Macaranga tanarius extract with rich sources of raw materials and simple preparation process in order to solve the defects of lack of resources and high price of the existing cancer drug paclitaxel

Method used

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  • Preparation method and application of macaranga tanarius extract
  • Preparation method and application of macaranga tanarius extract
  • Preparation method and application of macaranga tanarius extract

Examples

Experimental program
Comparison scheme
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Embodiment 1

[0027] The embodiment 1 of the preparation method of Macaranga tanarius extract of the present invention comprises the following steps:

[0028] Step 1, take the naturally dried leaves of Macaranga tanarius and dry them at 100°C, then pulverize and sieve to obtain Macaranga tanarius leaf powder;

[0029] Step 2, put the Macaranga tanarius leaf powder obtained in Step 1 into a beaker, add 1000-2000ml of distilled water per 100g of Macaranga tanarius leaf powder, then stir, heat and boil under normal pressure, continue decocting for 1-2 hours after boiling, and then Obtain the first filtrate and the first filter residue of the Macaranga tanarius extract after filtering through three layers of medical gauze;

[0030] Step 3, repeat step 2 twice for the first filter residue of step 2, and obtain the second filtrate of Macaranga tanarius extract, the second filter residue, and the third filtrate and third filter residue of Macaranga tanarius extract in sequence;

[0031] Step 4: C...

Embodiment 2

[0068] Example 2 of the preparation method of the Macaranga tanarius extract of the present invention, on the basis of Example 1, the features not explained in this example are explained in Example 1, and will not be repeated here. The difference between this embodiment and embodiment 1 is:

[0069] The preparation method of Macaranga tanarius extract comprises the following steps:

[0070] Step 1, take the naturally dried leaves of Macaranga tanarius, dry them at 100°C, crush them, and pass through a 40-mesh sieve to obtain Macaranga tanarius leaf powder;

[0071] Step 2: Weigh 200g Macaranga tanarius leaf powder into a 3000ml beaker, add 2000ml distilled water, then stir, heat and boil under normal pressure, continue decocting for 1 hour after boiling, and then filter through eight layers of medical gauze to obtain Macaranga tanarius extract The first filtrate and the first filter residue;

[0072] Step 3, repeating the above-mentioned first filter residue in step 2 twice ...

Embodiment 3

[0076] Example 3 of the preparation method of the Macaranga tanarius extract of the present invention, on the basis of Example 1, the features not explained in this example are explained in Example 1, and will not be repeated here. The difference between this embodiment and embodiment 1 is:

[0077] The preparation method of Macaranga tanarius extract comprises the following steps:

[0078] Step 1, take the naturally dried leaves of Macaranga tanarius, dry them at 100°C, crush them, and pass through a 40-mesh sieve to obtain Macaranga tanarius leaf powder;

[0079] Step 2: Weigh 200g of Macaranga tanarius leaf powder into a 3000ml beaker, add 2000ml of distilled water, then stir, heat and boil under normal pressure, continue decocting for 2 hours after boiling, and then filter through eight layers of medical gauze to obtain Macaranga tanarius extract The first filtrate and the first filter residue;

[0080] Step 3, repeating the above-mentioned first filter residue in step 2...

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Abstract

The invention relates to the technical field of natural medicaments, and in particular relates to a preparation method and application of macaranga tanarius extract. The preparation method comprises the following steps: baking naturally aired macaranga tanarius leaves at 100 DEG C, crushing and screening to obtain macaranga tanarius leave powder; adding 1000 to 2000 ml of distilled water in every100g of macaranga tanarius leave powder, stirring, heating and heating and boiling at normal pressure, continuing decocting for 1 to 2 hours after the solution is boiled, and filtering by using an eight-layer medical gauze to obtain first filtrate and first filter residues of the macaranga tanarius extract; repeating the performed operations twice on the first filter residues to obtain second filtrate and third filtrate of the macaranga tanarius extract; and combining the first filtrate of the macaranga tanarius extract, the second filtrate of the macaranga tanarius extract and the third filtrate of the macaranga tanarius extract, and distilling and concentrating the filtrate at reduced pressure to obtain extractum. The macaranga tanarius extract has remarkable treatment effect of resisting colon cancer, has wide raw material sources and simpleness in extraction process, is easy for scale production, and is beneficial to popularization for numerous patients.

Description

technical field [0001] The invention relates to the technical field of natural medicines, in particular to a preparation method and application of Macaranga tanarius extract. Background technique [0002] Colon cancer is a malignant tumor with high incidence in human beings. Its incidence rate has been on the rise and has risen to the third place in the incidence of malignant tumors in the world, and its mortality rate ranks second in the cause of death of malignant tumors. In my country, the mortality rate of colorectal cancer ranks fifth in the mortality rate of malignant tumors, seriously endangering human health. Governments, research institutes and pharmaceutical companies all attach great importance to and make huge investments in anti-colon cancer drugs. [0003] At present, the most valuable cancer drug recognized in the world is paclitaxel, which is a complex metabolite in the genus Taxus. The extract is isolated from the bark of Taxus, and its content in the bark ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P35/00A61K127/00
Inventor 赵肃清何带桂周代营张焜郑杰陈伟强温桂萍
Owner 广东瀚森生物科技有限公司
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