Chinese medicinal compound preparation for treating IgA (Immunoglobulin A) nephropathy and preparation method thereof

Abstract

The invention relates to a compound Chinese medicinal preparation for treating IgA (Immunoglobulin A) nephropathy. The compound Chinese medicinal preparation comprises the following Chinese medicinal raw materials by weight: 13-17 grams of astragalus, 8-12 grams of rehmannia root, 8-12 grams of red-rooted salvia root, 8-12 grams of common bletilla pseudobulb, 2-4 grams of cicada shell, 8-12 grams of garden burnet root, 16-24 grams of cogongrass rhizome and 2-4 grams of Chinese caterpillar fungus (brewed). A preparation method of the compound Chinese medicinal preparation comprises the following steps of: cleaning the eight types of medicinal materials; mixing proportionally; adding water in an amount which is 6-8 times the total weight of the medicinal materials or 70 percent by volume of ethanol for decocting for three times, every time for 40 minutes; combining decoction solutions obtained in the three times; filtering; and concentrating to obtain a liquid extract of which the specific weight is 1.21 at 60 DEG C. The compound Chinese medicinal preparation can be prepared into any pharmaceutical dosage form, such as tablets, capsules, granules, oral liquid, pills and syrup with the conventional preparation process. The compound Chinese medicinal preparation prepared with the method has the advantages of great reduction in the concentrations of albuminuria and hematuria of patient suffering from IgA nephropathy, great improvement on the kidney function, remarkable curative effect and great reduction in side effects and untoward reactions.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating IgA nephropathy and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] IgA nephropathy is the most common primary glomerulonephritis at home and abroad. It refers to the diffuse granular or agglomerated deposition of IgA or IgA-based immunoglobulin in the glomerular mesangium and capillary loops. A series of clinical and pathological changes. The disease accounts for 10%-20% of primary glomerular diseases, and the incidence in Asian countries such as China, Japan, and Singapore is relatively high, at 45%-50%, and after 20 years of disease activity, 20%-30% of the The patient progressed to renal failure. The clinical manifestations are diverse, the severity of histological changes is different, and the prognosis is also very different. The clinical manifestations are significant protei...

AI Technical Summary

Problems solved by technology

[0003] The existing Western medicines for the treatment of IgA nephropathy have the disadvantages of unsatisfactory curative effect, large side effects, and many adverse reactions.