Chinese medicinal compound preparation for treating IgA (Immunoglobulin A) nephropathy and preparation method thereof
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A preparation and kidney disease technology, applied in the field of traditional Chinese medicine preparations, can solve problems such as large side effects, many adverse reactions, and unsatisfactory curative effects, and achieve the effect of improving renal function, significant curative effect, and reducing side effects and adverse reactions
Inactive Publication Date: 2012-03-14
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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[0003] The existing Western medicines for the treatment of IgA nephropathy have the dis...
Method used
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Embodiment 1
[0011] A compound traditional Chinese medicine preparation for treating IgA nephropathy, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Astragalus 13, Shengdi 8, Salvia miltiorrhiza 8, Baiji 8, cicada slough 2, Burnet 8, Imperata rhizome 16, and Cordyceps sinensis (chong) 2.
[0012] The preparation method is to wash the above 8 medicinal materials, mix them in proportion, add 6 times the total weight of the medicinal materials, and decoct them for 3 times, each time for 40 minutes, combine the decoctions for 3 times, filter, and concentrate to obtain 60°C It is a liquid extract with a specific gravity of 1.21.
Embodiment 2
[0014] A compound traditional Chinese medicine preparation for treating IgA nephropathy, comprising the following traditional Chinese medicine raw materials in the following weight proportions: 15 pieces of Astragalus membranaceus, 10 pieces of Rehmannia root, 10 pieces of Salvia miltiorrhiza, 10 pieces of Baiji, 3 pieces of cicada slough, 10 pieces of Burnet elm, 20 pieces of Imperata rhizome, and 3 pieces of Cordyceps sinensis (Chong).
[0015] All the other are with embodiment 1.
Embodiment 3
[0017] A compound traditional Chinese medicine preparation for treating IgA nephropathy, comprising the following traditional Chinese medicine raw materials in the following weight proportions: Astragalus 17, Shengdi 12, Salvia miltiorrhiza 12, Baiji 12, Cicada slough 4, Burnet elm 12, Imperata radix 24, Cordyceps sinensis (Chong) 4.
[0018] The preparation method is to wash the above 8 medicinal materials, mix them in proportion, add 6 times the total weight of the medicinal materials and decoct 3 times in ethanol with a volume ratio of 70%, 40 minutes each time, combine the 3 decoction liquids, filter, and Concentrate to obtain a liquid extract with a specific gravity of 1.21 at 60°C.
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Abstract
The invention relates to a compound Chinese medicinal preparation for treating IgA (Immunoglobulin A) nephropathy. The compound Chinese medicinal preparation comprises the following Chinese medicinal raw materials by weight: 13-17 grams of astragalus, 8-12 grams of rehmannia root, 8-12 grams of red-rooted salvia root, 8-12 grams of common bletilla pseudobulb, 2-4 grams of cicada shell, 8-12 grams of garden burnet root, 16-24 grams of cogongrass rhizome and 2-4 grams of Chinese caterpillar fungus (brewed). A preparation method of the compound Chinese medicinal preparation comprises the following steps of: cleaning the eight types of medicinal materials; mixing proportionally; adding water in an amount which is 6-8 times the total weight of the medicinal materials or 70 percent by volume of ethanol for decocting for three times, every time for 40 minutes; combining decoction solutions obtained in the three times; filtering; and concentrating to obtain a liquid extract of which the specific weight is 1.21 at 60 DEG C. The compound Chinese medicinal preparation can be prepared into any pharmaceutical dosage form, such as tablets, capsules, granules, oral liquid, pills and syrup with the conventional preparation process. The compound Chinese medicinal preparation prepared with the method has the advantages of great reduction in the concentrations of albuminuria and hematuria of patient suffering from IgA nephropathy, great improvement on the kidney function, remarkable curative effect and great reduction in side effects and untoward reactions.
Description
technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating IgA nephropathy and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] IgA nephropathy is the most common primary glomerulonephritis at home and abroad. It refers to the diffuse granular or agglomerated deposition of IgA or IgA-based immunoglobulin in the glomerular mesangium and capillary loops. A series of clinical and pathological changes. The disease accounts for 10%-20% of primary glomerular diseases, and the incidence in Asian countries such as China, Japan, and Singapore is relatively high, at 45%-50%, and after 20 years of disease activity, 20%-30% of the The patient progressed to renal failure. The clinical manifestations are diverse, the severity of histological changes is different, and the prognosis is also very different. The clinical manifestations are significant protei...
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Application Information
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